Metformin mediates neuroprotection and attenuates hearing loss in experimental pneumococcal meningitis

[1] McIntyre PB(2012)Effect of vaccines on bacterial meningitis worldwide Lancet 380 1703-1711

[2] O’Brien KL(2018)Global, regional, and national burden of meningitis, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 Lancet Neurol 17 1061-1082

[3] Greenwood B(2010)Global and regional risk of disabling sequelae from bacterial meningitis: a systematic review and meta-analysis Lancet Infect Dis 10 317-328

[4] van de Beek D(2011)Pathogenesis and pathophysiology of pneumococcal meningitis Clin Microbiol Rev 24 557-591

[5] Kassebaum NJ(2016)Neurological sequelae of bacterial meningitis J Inf Secur 73 18-27

[6] Blake N(2017)pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion J Exp Med 214 1619-1630

[7] Glennie L(1995)Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor Nature 377 435-438

[8] Wright C(2000)The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells Cell 102 827-837

[9] Nichols E(2014)Platelet endothelial cell adhesion molecule-1, a putative receptor for the adhesion of Streptococcus pneumoniae to the vascular endothelium of the blood-brain barrier Infect Immun 82 3555-3566

[10] Edmond K(2014)Streptococcus pneumoniae interacts with pIgR expressed by the brain microvascular endothelium but does not co-localize with PAF receptor PLoS One 9 e97914-209

[1] McIntyre PB(2012)Effect of vaccines on bacterial meningitis worldwide Lancet 380 1703-1711

[2] O’Brien KL(2018)Global, regional, and national burden of meningitis, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 Lancet Neurol 17 1061-1082

[3] Greenwood B(2010)Global and regional risk of disabling sequelae from bacterial meningitis: a systematic review and meta-analysis Lancet Infect Dis 10 317-328

[4] van de Beek D(2011)Pathogenesis and pathophysiology of pneumococcal meningitis Clin Microbiol Rev 24 557-591

[5] Kassebaum NJ(2016)Neurological sequelae of bacterial meningitis J Inf Secur 73 18-27

[6] Blake N(2017)pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion J Exp Med 214 1619-1630

[7] Glennie L(1995)Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor Nature 377 435-438

[8] Wright C(2000)The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells Cell 102 827-837

[9] Nichols E(2014)Platelet endothelial cell adhesion molecule-1, a putative receptor for the adhesion of Streptococcus pneumoniae to the vascular endothelium of the blood-brain barrier Infect Immun 82 3555-3566

[10] Edmond K(2014)Streptococcus pneumoniae interacts with pIgR expressed by the brain microvascular endothelium but does not co-localize with PAF receptor PLoS One 9 e97914-209