The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors

被引：0
作者：
Jae-Min Yuk
Dong-Min Shin
Hye-Mi Lee
Jwa-Jin Kim
Sun-Woong Kim
Hyo Sun Jin
Chul-Su Yang
Kyeong Ah Park
Dipanjan Chanda
Don-Kyu Kim
Song Mei Huang
Sang Ki Lee
Chul-Ho Lee
Jin-Man Kim
Chang-Hwa Song
Soo Young Lee
Gang Min Hur
David D Moore
Hueng-Sik Choi
Eun-Kyeong Jo
机构：
[1] Chungnam National University School of Medicine,Department of Microbiology
[2] Infection Signaling Network Research Center,Department of Pharmacology
[3] Chungnam National University School of Medicine,Department of Pathology
[4] Chungnam National University School of Medicine,Department of Sports Science
[5] National Creative Research Initiatives Center for Nuclear Receptor Signals,Department of Bioinspired Science
[6] Hormone Research Center,Department of Molecular and Cellular Biology
[7] School of Biological Sciences and Technology,undefined
[8] Chonnam National University,undefined
[9] Chungnam National University School of Medicine,undefined
[10] College of Natural Science,undefined
[11] Chungnam National University,undefined
[12] Animal Model Center,undefined
[13] Korea Research Institute of Bioscience and Biotechnology,undefined
[14] College of Life Science,undefined
[15] Ewha Womans University,undefined
[16] Baylor College of Medicine,undefined
[17] Present address: Department of Molecular Microbiology and Immunology,undefined
[18] University of Southern California,undefined
[19] Keck School of Medicine,undefined
[20] Los Angeles,undefined
[21] California,undefined
[22] USA.,undefined
来源：
Nature Immunology | 2011年 / 12卷
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摘要：
The orphan nuclear receptor SHP is a transcriptional corepressor in the liver. Jo and colleagues show that it also acts to negatively regulate Toll-like receptor signaling at multiple levels.
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页码：742 / 751
页数：9
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