Polyurethane Modified with Plasma-Ion Implantation for Medical Applications

被引：6

作者：

Chudinov V.S. ^{[1
]}

Kondyurina I.V. ^{[2
]}

Shardakov I.N. ^{[1
]}

Svistkov A.L. ^{[1
]}

Osorgina I.V. ^{[3
]}

Kondyurin A.V. ^{[4
]}

机构：

[1] Institute of Continuous Media Mechanics, Ural Branch, Russian Academy of Sciences, ul. Akademika Koroleva 1, Perm

[2] School of Medicine, University of Sydney, Sydney

[3] Perm State University, ul. Bukireva 15, Perm

[4] School of Physics, University of Sydney, Sydney

来源：

Biophysics | 2018年 / 63卷 / 3期

关键词：

biocompatibility; carbonized layer; implant; plasma-ion implantation; polyurethane;

D O I：

10.1134/S0006350918030053

中图分类号：

学科分类号：

摘要：

Medical polyurethane was treated with 20 keV nitrogen ions with a fluence of 1014–1016 ions/cm2. The modified polyurethane has a layered structure consisting of a 70-nm carbonized layer and a partly depolymerized layer below the carbonized layer. The high level of activity of the polyurethane due to free radicals provides stable adhesion of protein molecules to the surface layer of the polyurethane. The high level of hydrophilicity of the modified polyurethane surface preserves the biological activity of the attached proteins. This contributes to the attachment of endothelial cells to the polyurethane surface and their proliferation. Thus, this modified polyurethane can be used as a material for soft-tissue medical implants. © 2018, Pleiades Publishing, Inc.

引用

页码：330 / 339

页数：9

共 46 条

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