Small bowel bacterial overgrowth: A negative factor in gut adaptation in pediatric SBS

被引：51
作者：
Cole C.R. [1 ]
Ziegler T.R. [1 ]
机构：
[1] Division of Gastroenterology Hepatology and Nutrition, Department of Pediatrics, Altanta, GA 30322
来源：
Current Gastroenterology Reports | 2007年 / 9卷 / 6期
基金：
美国国家卫生研究院;
关键词：
Bile Acid; Enteral Nutrition; Short Bowel Syndrome; Bacterial Overgrowth; Rifaximin;
D O I：
10.1007/s11894-007-0059-3
中图分类号：
学科分类号：
摘要：
Small bowel bacterial overgrowth (SBBO) is common in infants and children with short bowel syndrome (SBS). Its occurrence is due to alterations in anatomy, motility, and secretion, which promote the abnormal growth of bacteria. SBBO is associated with significant clinical problems, including prolonged dependence on parenteral nutrition, liver injury, and malabsorption. A major clinical challenge is in making the correct diagnosis of bacterial overgrowth. Management of this disorder is still poorly understood and should be evaluated adequately. This review addresses the current understanding of bacteria in the intestines and issues related to bacterial overgrowth in pediatric SBS. Copyright © 2007 by Current Medicine Group LLC.
引用
收藏
页码：456 / 462
页数：6
相关论文
共 52 条
[1]  
Buchman A.L., Scolapio J., Fryer J., AGA technical review on short bowel syndrome and intestinal transplantation, Gastroenterology, 124, pp. 1111-1134, (2003)
[2]  
Schwartz M.Z., Maeda K., Short bowel syndrome in infants and children, Pediatr Clin North Am, 32, pp. 1265-1279, (1985)
[3]  
Wales P.W., de Silva N., Kim J.H., Et al., Neonatal short bowel. syndrome: A cohort study, J Pediatr Surg, 40, pp. 755-762, (2005)
[4]  
O'Keefe S.J., Buchman A.L., Fishbein T.M., Et al., Short bowel syndrome and intestinal failure: Consensus definitions and overview, Clin Gastroenterol Hepatol, 4, pp. 6-10, (2006)
[5]  
Wales P.W., de Silva N., Kim J., Et al., Neonatal short bowel syndrome: Population-based estimates of incidence and mortality rates, J Pediatr Surg, 39, pp. 690-695, (2004)
[6]  
Kocoshis S.A., Short bowel and long life: No longer mutually exclusive, J Pediatr, 145, pp. 147-148, (2004)
[7]  
Sondheimer J.M., Cadnapaphornchai M., Sontag M., Zerbe G.O., Predicting the duration of dependence on parenteral nutrition after neonatal intestinal resection, J Pediatr, 132, pp. 80-84, (1998)
[8]  
Javid P.J., Collier S., Richardson D., Et al., The role of enteral nutrition in the reversal of parenteral nutrition-associated liver dysfunction in infants, J Pediatr Surg, 40, pp. 1015-1018, (2005)
[9]  
Andorsky D.J., Lund D.P., Lillehei C.W., Et al., Nutritional and other postoperative management of neonates with short bowel syndrome correlates with clinical outcomes, J Pediatr, 139, pp. 27-33, (2001)
[10]  
Richards D.M., Irving M.H., Cost-utility analysis of home parenteral nutrition, Br J Surg, 83, pp. 1226-1229, (1996)
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