A Model of Hyperhomocysteine-Induced Endothelial Dysfunction in Rats

被引：0
|
作者：
M. V. Korokin
M. V. Pokrovskiy
O. O. Novikov
O. S. Gudyrev
V. V. Gureev
T. A. Denisyuk
L. V. Korokina
L. M. Danilenko
V. A. Ragulina
E. A. Konovalova
A. S. Belous
机构：
[1] Ministry of Health Care and Social Development of the Russian Federation,Kursk State Medical University
来源：
Bulletin of Experimental Biology and Medicine | 2011年 / 152卷
关键词：
endothelial dysfunction; methionine; homocysteine; hyperhomocysteinemia;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Intragastric methionine (3 g/kg daily for 7 days) elevates homocysteine concentration and increases the endothelial dysfunction coefficient. This protocol of methionine treatment is an adequate model of hyperhomocysteine-induced endothelial dysfunction and can be used for studies of the endothelio- and cardioprotective effects of drugs.
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页码：213 / 215
页数：2
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