Structural basis for the Rho- and phosphoinositide-dependent localization of the exocyst subunit Sec3

被引：0
作者：
Masami Yamashita
Kazuo Kurokawa
Yusuke Sato
Atsushi Yamagata
Hisatoshi Mimura
Azusa Yoshikawa
Ken Sato
Akihiko Nakano
Shuya Fukai
机构：
[1] Structural Biology Laboratory,Life Science Division
[2] Synchrotron Radiation Research Organization and Institute of Molecular and Cellular Biosciences,Department of Medical Genome Sciences
[3] The University of Tokyo,Department of Biological Information
[4] Graduate School of Frontier Sciences,Department of Life Sciences
[5] The University of Tokyo,Department of Biological Sciences
[6] Molecular Membrane Biology Laboratory,undefined
[7] RIKEN Advanced Science Institute,undefined
[8] Graduate School of Bioscience and Technology,undefined
[9] Tokyo Institute of Technology,undefined
[10] Graduate School of Arts and Sciences,undefined
[11] The University of Tokyo,undefined
[12] Meguro-ku,undefined
[13] Tokyo,undefined
[14] Japan.,undefined
[15] Graduate School of Science,undefined
[16] The University of Tokyo,undefined
[17] Bunkyo-ku,undefined
[18] Tokyo,undefined
[19] Japan.,undefined
来源：
Nature Structural & Molecular Biology | 2010年 / 17卷
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摘要：
The Sec3 subunit of the yeast exocyst complex tethers secretory vesicles to the plasma membrane for exocytosis through interactions with a small GTPase and PtdIns(4,5)P2 in the target membrane. A new study describes the crystal structure of the N-terminal Rho1/Cdc42- and PtdIns(4,5)P2-binding domain of Sec3 in complex with Rho1.
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页码：180 / 186
页数：6
相关论文
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