Acupuncture and moxibustion as complementary therapy in Crohn's disease

被引：2
作者：
Stefanie Joos
B. Brinkhaus
C. Maluche
N. Maupai
R. Kohnen
E. Hahn
D. Schuppan
机构：
[1] Medizinische Klinik I, F.-Alexander-Univ. Erlangen-Nurnberg, Erlangen
[2] IMEREM, Inst. for Med. Res. Mgmt./Biometr., Nürnberg
[3] Sekt. Allg.Med./Versorgungsforsch., Universität Heidelberg, Heidelberg
[4] Inst. Sozialmed./Epidemiol./G., Charité, Berlin
[5] Universität Heidelberg, Medizinische Klinik und Poliklinik, Sekt. Allg.Med. Versorgungsforsch., D-69115 Heidelberg
来源：
Deutsche Zeitschrift für Akupunktur | 2005年 / 48卷 / 1期
关键词：
Acupuncture; Complementary medicine; Crohn's disease; Crohn's disease activity index; Inflammatory bowel disease; Traditional Chinese Medicine;
D O I：
10.1078/0415-6412-00090
中图分类号：
学科分类号：
摘要：
Background: Acupuncture has traditionally been used in the treatment of inflammatory bowel disease in China and is increasingly applied in Western countries. The aim of the study was to investigate the efficacy of acupuncture in the treatment of active Crohn's disease. Methods: Prospective, randomized, controlled, single-blind clinical trial. Change in Crohn's Disease Activity Index (CDAI) was used after treatment as main outcome measure, changes in quality of life and general well-being, serum markers of inflammation (α1-acid glycoprotein, C-reactive protein) as secondary outcome measures. 51 patients with mild to moderately active Crohn's disease were treated in a single center for complementary medicine by three trained acupuncterists and randomly assigned to receive either traditional acupuncture (TCM group, n = 27) or control treatment at non-acupuncture points (control group, n = 24). Patients were treated in 10 sessions over a period of 4 weeks and followed up for 12 weeks. Results: In the TCM group CDAI decreased from 250 (± 51) to 163 (± 56) points as compared with a mean decrease from 220 (± 42) to 181 (± 46) points in the control group (TCM vs. control group: p = 0.003). In both groups these changes were associated with improvements in general well-being and quality of life. α1-acid glycoprotein concentration fell significantly only in the TCM group (p = 0.046). Conclusions: Apart from a marked placebo-effect traditional acupuncture offers an additional therapeutic benefit in patients with mild to moderately active Crohn's disease.
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页码：6 / 17
页数：11
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