Protocol of a randomised delayed-start double-blind placebo-controlled multi-centre trial for Levodopa in EArly Parkinson’s disease: the LEAP-study

被引:0
|
作者
Constant V. M. Verschuur
S. R. Suwijn
B. Post
M. Dijkgraaf
B. R. Bloem
J. J. van Hilten
T. van Laar
G. Tissingh
G. Deuschl
A. E. Lang
R. J. de Haan
R. M. A. de Bie
机构
[1] University of Amsterdam,Department of Neurology, Academic Medical Center
[2] Radboud University Medical Center,Department of Neurology, Donders Institute for Brain, Cognition and Behavior
[3] Clinical Research Unit,Academic Medical Center
[4] Leiden University Medical Center,Department of Neurology
[5] University Medical Center Groningen,Department of Neurology
[6] Atrium-Orbis Medical Center Heerlen/Sittard,Department of Neurology
[7] University Medical Center Schleswig-Holstein,Department of Neurology
[8] University of Toronto,The Edmond J. Safra Program in Parkinson’s Disease and Morton and Gloria Shulman Movement Disorders Center, Toronto Western Hospital
来源
BMC Neurology | / 15卷
关键词
Parkinson’s disease; Levodopa; Randomised delayed-start placebo-controlled trial; Disease modifying;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] Protocol of a randomised delayed-start double-blind placebo-controlled multi-centre trial for Levodopa in EArly Parkinson's disease: the LEAP-study
    Verschuur, Constant V. M.
    Suwijn, S. R.
    Post, B.
    Dijkgraaf, M.
    Bloem, B. R.
    van Hilten, J. J.
    van Laar, T.
    Tissingh, G.
    Deuschl, G.
    Lang, A. E.
    de Haan, R. J.
    de Bie, R. M. A.
    BMC NEUROLOGY, 2015, 15
  • [2] A Double-Blind, Delayed-Start Trial of Rasagiline in Parkinson's Disease
    Olanow, C. Warren
    Rascol, Olivier
    Hauser, Robert
    Feigin, Paul D.
    Jankovic, Joseph
    Lang, Anthony
    Langston, William
    Melamed, Eldad
    Poewe, Werner
    Stocchi, Fabrizio
    Tolosa, Eduardo
    NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (13) : 1268 - 1278
  • [3] Transdermal Rotigotine in Early Stage Parkinson's Disease: A Randomized, Double-blind, Placebo-controlled Trial
    Mizuno, Yoshikuni
    Nomoto, Masahiro
    Kondo, Tomoyoshi
    Hasegawa, Kazuko
    Murata, Miho
    Takeuchi, Masahiro
    Ikeda, Junji
    Tomida, Takayuki
    Hattori, Nobutaka
    MOVEMENT DISORDERS, 2013, 28 (10) : 1447 - 1450
  • [4] A Randomized, Double-Blind, Placebo-Controlled Trial of Levetiracetam for Dyskinesia in Parkinson's Disease
    Wong, Kitty K.
    Alty, Jane E.
    Goy, Amanda G.
    Raghav, Sanjay
    Reutens, David C.
    Kempster, Peter A.
    MOVEMENT DISORDERS, 2011, 26 (08) : 1552 - 1555
  • [5] Levodopa improves physical fatigue in Parkinson's disease: A double-blind, placebo-controlled, crossover study
    Lou, JS
    Kearns, G
    Benice, T
    Oken, B
    Sexton, G
    Nutt, J
    MOVEMENT DISORDERS, 2003, 18 (10) : 1108 - 1114
  • [6] Levetiracetam for levodopa-induced dyskinesia in Parkinson's disease: a randomized, double-blind, placebo-controlled trial
    Wolz, Martin
    Lohle, Matthias
    Strecker, Karl
    Schwanebeck, Uta
    Schneider, Christine
    Reichmann, Heinz
    Graehlert, Xina
    Schwarz, Johannes
    Storch, Alexander
    JOURNAL OF NEURAL TRANSMISSION, 2010, 117 (11) : 1279 - 1286
  • [7] Levetiracetam for levodopa-induced dyskinesia in Parkinson’s disease: a randomized, double-blind, placebo-controlled trial
    Martin Wolz
    Matthias Löhle
    Karl Strecker
    Uta Schwanebeck
    Christine Schneider
    Heinz Reichmann
    Xina Grählert
    Johannes Schwarz
    Alexander Storch
    Journal of Neural Transmission, 2010, 117 : 1279 - 1286
  • [8] Ursodeoxycholic acid as a novel disease-modifying treatment for Parkinson's disease: protocol for a two-centre, randomised, double-blind, placebo-controlled trial, The 'UP' study
    Payne, Thomas
    Sassani, Matilde
    Buckley, Ellen
    Moll, Sarah
    Anton, Adriana
    Appleby, Matthew
    Maru, Seema
    Taylor, Rosie
    McNeill, Alisdair
    Hoggard, N.
    Mazza, Claudia
    Wilkinson, Iain D.
    Jenkins, Thomas
    Foltynie, Thomas
    Bandmann, O.
    BMJ OPEN, 2020, 10 (08):
  • [9] A double-blind, placebo-controlled and longitudinal study of riluzole in early Parkinson's disease
    Jankovic, J
    Hunter, C
    PARKINSONISM & RELATED DISORDERS, 2002, 8 (04) : 271 - 276
  • [10] A Randomized, Double-Blind, Placebo-Controlled Trial of Camicinal in Parkinson's Disease
    Marrinan, Sarah L.
    Otiker, Tal
    Vasist, Lakshmi S.
    Gibson, Rachel A.
    Sarai, Bhopinder K.
    Barton, Matthew E.
    Richards, Duncan B.
    Hellstrom, Per M.
    Nyholm, Dag
    Dukes, George E.
    Burn, David J.
    MOVEMENT DISORDERS, 2018, 33 (02) : 329 - 332