FAK inhibition radiosensitizes pancreatic ductal adenocarcinoma cells in vitro

被引:0
作者
A. Allam Mohamed
Andreas Thomsen
Marie Follo
Costantinos Zamboglou
Peter Bronsert
Hanan Mostafa
Aber Amen
Mohamed Mekawy
Anca L. Grosu
Thomas B. Brunner
机构
[1] University of Freiburg,Department of Radiation Oncology, Medical Center, Faculty of Medicine
[2] University of Freiburg,Department of Medicine I, Medical Center, Faculty of Medicine
[3] University of Freiburg,Institute for Surgical Pathology, Medical Center, Faculty of Medicine
[4] Assiut University Hospitals,Clinical Oncology and Nuclear Medicine Department
[5] German Cancer Consortium (DKTK),Partner Site Freiburg
[6] RWTH Aachen University,Department of Radiation Oncology
[7] University of Magdeburg,Department of Radiation Oncology
来源
Strahlentherapie und Onkologie | 2021年 / 197卷
关键词
Pancreatic ductal adenocarcinoma; Focal adhesion kinase; Radiosensitization; Pancreatic stellate cell; Microenvironment; Stroma;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:27 / 38
页数:11
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  • [1] Jemal A(2009)Cancer Statistics, 2009 CA Cancer J Clin 59 225-249
  • [2] Siegel RL(2015)Cancer statistics, 2015 CA Cancer J Clin 65 5-29
  • [3] Miller KD(2008)The Activated Stroma Index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma Clin Gastroenterol Hepatol 6 1155-1161
  • [4] Jemal A(2000)Role of extracellular matrix assembly in interstitial transport in solid tumors Cancer Res 60 2497-2503
  • [5] Erkan M(2017)Pancreatic stellate cells in pancreatic cancer: in focus Pancreatology 16 1727-1733
  • [6] Netti PA(2009)Pretreatment assessment of resectable and borderline resectable pancreatic cancer: expert consensus statement Ann Surg Oncol 12 167-172
  • [7] Berk DA(2014)Evolving treatment options for locally advanced unresectable pancreatic ductal adenocarcinoma J Natl Compr Canc Netw 19 7461-7471
  • [8] Swartz MA(2013)Combined radiochemotherapy in patients with locally advanced pancreatic cancer: a meta-analysis World J Gastroenterol 194 627-637
  • [9] Grodzinsky AJ(2018)Nonmetastatic pancreatic cancer Strahlenther. Onkol. 193 433-443
  • [10] Jain RK(2017)Stereotactic body radiotherapy (SBRT) in recurrent or oligometastatic pancreatic cancer Strahlenther Onkol 194 835-842