Good guys gone bad: exTreg cells promote autoimmune arthritis

被引：0

作者：

Nicole Joller

Vijay K Kuchroo

机构：

[1] Nicole Joller and Vijay K. Kuchroo are at the Center for Neurologic Diseases,

[2] Brigham and Women's Hospital,undefined

[3] Harvard Medical School,undefined

[4] Boston,undefined

[5] Massachusetts,undefined

[6] USA.,undefined

来源：

Nature Medicine | 2014年 / 20卷

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摘要：

Under most circumstances, Foxp3+ regulatory T (Treg) cells are a stable T cell population essential for maintaining self-tolerance. A study now shows that the inflammatory environment in autoimmune arthritis induces conversion of a subset of Foxp3+ T cells into interleukin-17–producing cells that contribute to disease pathogenesis (pages 62–68).

引用

页码：15 / 17

页数：2

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