Lower prevalence of Lynch syndrome in colorectal cancer patients in a Japanese hospital-based population

Mizoue T(2014)Fourfold increased detection of Lynch syndrome by raising age limit for tumour genetic testing from 50 to 70 years is cost-effective Ann Oncol 25 2001-2007

Heald B(2012)A state-wide population-based program for detection of lynch syndrome based upon immunohistochemical and molecular testing of colorectal tumours Fam Cancer 11 1-6

Plesec T(2007)Performance of different microsatellite marker panels for detection of mismatch repair-deficient colorectal tumors J Natl Cancer Inst 99 244-252

Liu X(2005)Microsatellite instability testing in colorectal carcinoma: choice of markers affects sensitivity of detection of mismatch repair-deficient tumors Clin Cancer Res 11 2180-2187

Pai R(2009)Immunohistochemistry as first-line screening for detecting colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: a 2-antibody panel may be as predictive as a 4-antibody panel Am J Surg Pathol 33 1639-1645

Patil D(2012)Identification of cancer patients with Lynch syndrome: clinically significant discordances and problems in tissue-based mismatch repair testing Cancer Prev Res (Phila) 5 320-327

Moline J(2003)Microsatellite instability in colorectal carcinoma. The comparison of immunohistochemistry and molecular biology suggests a role for hMSH6 immunostaining Arch Pathol Lab Med 127 694-700

Pérez-Carbonell L(2002)Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors J Clin Oncol 20 1043-1048

Ruiz-Ponte C(2011)Microsatellite instability in the management of colorectal cancer Expert Rev Gastroenterol Hepatol 5 385-399

Guarinos C(2011)Challenges in the identification of MSH6-associated colorectal cancer: rectal location, less typical histology, and a subset with retained mismatch repair function Am J Surg Pathol 35 1391-1399

Mizoue T(2014)Fourfold increased detection of Lynch syndrome by raising age limit for tumour genetic testing from 50 to 70 years is cost-effective Ann Oncol 25 2001-2007

Heald B(2012)A state-wide population-based program for detection of lynch syndrome based upon immunohistochemical and molecular testing of colorectal tumours Fam Cancer 11 1-6

Plesec T(2007)Performance of different microsatellite marker panels for detection of mismatch repair-deficient colorectal tumors J Natl Cancer Inst 99 244-252

Liu X(2005)Microsatellite instability testing in colorectal carcinoma: choice of markers affects sensitivity of detection of mismatch repair-deficient tumors Clin Cancer Res 11 2180-2187

Pai R(2009)Immunohistochemistry as first-line screening for detecting colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: a 2-antibody panel may be as predictive as a 4-antibody panel Am J Surg Pathol 33 1639-1645

Patil D(2012)Identification of cancer patients with Lynch syndrome: clinically significant discordances and problems in tissue-based mismatch repair testing Cancer Prev Res (Phila) 5 320-327

Moline J(2003)Microsatellite instability in colorectal carcinoma. The comparison of immunohistochemistry and molecular biology suggests a role for hMSH6 immunostaining Arch Pathol Lab Med 127 694-700

Pérez-Carbonell L(2002)Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors J Clin Oncol 20 1043-1048

Ruiz-Ponte C(2011)Microsatellite instability in the management of colorectal cancer Expert Rev Gastroenterol Hepatol 5 385-399

Guarinos C(2011)Challenges in the identification of MSH6-associated colorectal cancer: rectal location, less typical histology, and a subset with retained mismatch repair function Am J Surg Pathol 35 1391-1399