Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation

被引：0
|
作者：
Ines Greco
Nicola Day
Joanna Riddoch-Contreras
Jane Reed
Hilkka Soininen
Iwona Kłoszewska
Magda Tsolaki
Bruno Vellas
Christian Spenger
Patrizia Mecocci
Lars-Olof Wahlund
Andrew Simmons
Julie Barnes
Simon Lovestone
机构：
[1] Institute of Psychiatry,King’s College London
[2] BioWisdom Ltd,now Instem Scientific
[3] University of Eastern Finland and University Hospital of Kuopio,3rd Department of Neurology, "G. Papanicolaou" Hospital
[4] Medical University of Lodz,UMR INSERM 1027, Gerontopole, CHU Toulouse
[5] Aristotle University of Thessaloniki,Department of Clinical Science, Intervention and Technology
[6] University of Toulouse,Institute of Gerontology and Geriatrics
[7] Karolinska Institutet,Department of Neurobiology, Care Sciences and Society
[8] University of Perugia,undefined
[9] Karolinska Institutet,undefined
[10] Currently at Somaxa Ltd and Abcodia Ltd,undefined
来源：
Journal of Translational Medicine | / 10卷
关键词：
Alzheimer’s disease; Proteomics; Biomarkers; Choline acetyltransferase (ChAt); Urokinase-type plasminogen activator receptor (PLAUR); Intelligence network; Bioinformatics; MRI; Literature mining;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Next-generation biomarker discovery in Alzheimer's disease using metabolomics - from animal to human studies
    Hurtado, Marina Olle
    Kohler, Isabelle
    de Lange, Elizabeth C. M.
    BIOANALYSIS, 2018, 10 (18) : 1525 - 1546
  • [42] Clinical and Biomarker Characteristics According to Clinical Spectrum of Alzheimer's Disease (AD) in the Validation Cohort of Korean Brain Aging Study for the Early Diagnosis and Prediction of AD
    Hwang, Jihye
    Jeong, Jee Hyang
    Yoon, Soo Jin
    Park, Kyung Won
    Kim, Eun-Joo
    Yoon, Bora
    Jang, Jae-Won
    Kim, Hee Jin
    Hong, Jin Yong
    Lee, Jong-Min
    Park, Hyuntae
    Kang, Ju-Hee
    Choi, Yong-Ho
    Park, Gilsoon
    Hong, Jinwoo
    Byun, Min Soo
    Yi, Dahyun
    Kim, Yu Kyeong
    Lee, Dong Young
    Choi, Seong Hye
    JOURNAL OF CLINICAL MEDICINE, 2019, 8 (03)
  • [43] Biomarker-guided clustering of Alzheimer's disease clinical syndromes
    Toschi, Nicola
    Lista, Simone
    Baldacci, Filippo
    Cavedo, Enrica
    Zetterberg, Henrik
    Blennow, Kaj
    Kilimann, Ingo
    Teipel, Stefan J.
    dos Santos, Antonio Melo
    Epelbaum, Stephane
    Lamari, Foudil
    Genthon, Remy
    Habert, Marie-Odile
    Dubois, Bruno
    Floris, Roberto
    Garaci, Francesco
    Vergallo, Andrea
    Hampel, Harald
    Afshar, Mohammad
    Aguilar, Lisi Flores
    Akman-Anderson, Leyla
    Arenas, Joaquin
    Babiloni, Claudio
    Baldacci, Filippo
    Batrla, Richard
    Benda, Norbert
    Black, Keith L.
    Bokde, Arun L. W.
    Bonuccelli, Ubaldo
    Broich, Karl
    Cacciola, Francesco
    Caraci, Filippo
    Castrillo, Juan
    Cavedo, Enrica
    Ceravolo, Roberto
    Chiesa, Patrizia A.
    Corvol, Jean-Christophe
    Cuello, Augusto Claudio
    Cummings, Jeffrey L.
    Depypere, Herman
    Dubois, Bruno
    Duggento, Andrea
    Emanuele, Enzo
    Escott-Price, Valentina
    Federoff, Howard
    Ferretti, Maria Teresa
    Fiandaca, Massimo
    Frank, Richard A.
    Garaci, Francesco
    Geerts, Hugo
    NEUROBIOLOGY OF AGING, 2019, 83 : 42 - 53
  • [44] The Evaluation of Clinical Applications for the Detection of the Alzheimer's Disease Biomarker GFAP
    Ozcelikay-Akyildiz, Goksu
    Karadurmus, Leyla
    Cetinkaya, Ahmet
    Uludag, Inci
    Ozcan, Burcu
    Unal, Mehmet Altay
    Sezginturk, Mustafa Kemal
    Ozkan, Sibel A.
    CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY, 2024,
  • [45] Secretases-related miRNAs in Alzheimer's disease: new approach for biomarker discovery
    Hajjari, Seyedeh Nazanin
    Mehdizadeh, Mehdi
    Sadigh-Eteghad, Saeed
    Shanehbandi, Dariush
    Teimourian, Shahram
    Baradaran, Behzad
    NEUROLOGICAL SCIENCES, 2017, 38 (11) : 1921 - 1926
  • [46] The Potential of Neurofilament Light as a Biomarker in Alzheimer's Disease
    Xiong, Yong-lan
    Meng, Tao
    Luo, Jing
    Zhang, Hua
    EUROPEAN NEUROLOGY, 2021, 84 (01) : 6 - 15
  • [47] Towards a Dynamic Biomarker Model in Alzheimer's Disease
    Mouiha, Abderazzak
    Duchesne, Simon
    JOURNAL OF ALZHEIMERS DISEASE, 2012, 30 (01) : 91 - 100
  • [48] Plasma neuregulin 1 as a synaptic biomarker in Alzheimer's disease: a discovery cohort study
    Vrillon, Agathe
    Mouton-Liger, Francois
    Martinet, Matthieu
    Cognat, Emmanuel
    Hourregue, Claire
    Dumurgier, Julien
    Bouaziz-Amar, Elodie
    Brinkmalm, Ann
    Blennow, Kaj
    Zetterberg, Henrik
    Hugon, Jacques
    Paquet, Claire
    ALZHEIMERS RESEARCH & THERAPY, 2022, 14 (01)
  • [49] Bridging the Gap between Gut Microbiota and Alzheimer's Disease: A Metaproteomic Approach for Biomarker Discovery in Transgenic Mice
    Ayan, Esra
    Demirci, Hasan
    Serdar, Muhittin Abdulkadir
    Palermo, Francesca
    Baykal, Ahmet Tarik
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (16)
  • [50] Proteomic landscape of Alzheimer's Disease: novel insights into pathogenesis and biomarker discovery (vol 16, 55, 2021)
    Bai, Bing
    Vanderwall, David
    Li, Yuxin
    Wang, Xusheng
    Poudel, Suresh
    Wang, Hong
    Dey, Kaushik Kumar
    Chen, Ping-Chung
    Yang, Ka
    Peng, Junmin
    MOLECULAR NEURODEGENERATION, 2021, 16 (01)
12345