Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation

被引：0
作者：
Ines Greco
Nicola Day
Joanna Riddoch-Contreras
Jane Reed
Hilkka Soininen
Iwona Kłoszewska
Magda Tsolaki
Bruno Vellas
Christian Spenger
Patrizia Mecocci
Lars-Olof Wahlund
Andrew Simmons
Julie Barnes
Simon Lovestone
机构：
[1] Institute of Psychiatry,King’s College London
[2] BioWisdom Ltd,now Instem Scientific
[3] University of Eastern Finland and University Hospital of Kuopio,3rd Department of Neurology, "G. Papanicolaou" Hospital
[4] Medical University of Lodz,UMR INSERM 1027, Gerontopole, CHU Toulouse
[5] Aristotle University of Thessaloniki,Department of Clinical Science, Intervention and Technology
[6] University of Toulouse,Institute of Gerontology and Geriatrics
[7] Karolinska Institutet,Department of Neurobiology, Care Sciences and Society
[8] University of Perugia,undefined
[9] Karolinska Institutet,undefined
[10] Currently at Somaxa Ltd and Abcodia Ltd,undefined
来源：
Journal of Translational Medicine | / 10卷
关键词：
Alzheimer’s disease; Proteomics; Biomarkers; Choline acetyltransferase (ChAt); Urokinase-type plasminogen activator receptor (PLAUR); Intelligence network; Bioinformatics; MRI; Literature mining;
D O I：
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摘要：
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[1]  
Lovestone S(2007)Proteomics of Alzheimer's disease: understanding mechanisms and seeking biomarkers Expert Rev Proteomics 4 227-238
[2]  
Guntert A(2011)Biomarkers for Alzheimer's disease therapeutic trials Prog Neurobiol 95 579-593
[3]  
Hye A(2010)Cerebrospinal fluid and plasma biomarkers in Alzheimer disease Nat Rev Neurol 6 131-144
[4]  
Lynham S(2009)A worldwide multicentre comparison of assays for cerebrospinal fluid biomarkers in Alzheimer's disease AnnClinBiochem 46 235-240
[5]  
Thambisetty M(2010)Blood-based biomarkers of Alzheimer's disease: challenging but feasible BiomarkMed 4 65-79
[6]  
Ward M(2010)Proteome-based plasma markers of brain amyloid-beta deposition in non-demented older individuals J Alzheimers Dis 22 1099-1109
[7]  
Hampel H(2010)Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease ArchGenPsychiatry 67 739-748
[8]  
Wilcock G(2012)The KUPKB: a novel Web application to access multiomics data on kidney disease FASEB J 26 2145-2153
[9]  
Andrieu S(2012)Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species Nucleic Acids Res 40 D71-75
[10]  
Aisen P(2010)AddNeuroMed–the European collaboration for the discovery of novel biomarkers for Alzheimer's disease Chem Res Toxicol 23 171-183
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