Is the use of sentient animals in basic research justifiable?

被引:22
作者
Greek R. [1 ]
Greek J. [1 ]
机构
[1] Americans For Medical Advancement, Goleta, CA 93117
基金
英国惠康基金; 英国医学研究理事会;
关键词
Basic Science Research; Sentient Animal; Nonmammalian Vertebrate; Informed Society; Basic Biomedical Research;
D O I
10.1186/1747-5341-5-14
中图分类号
学科分类号
摘要
Animals can be used in many ways in science and scientific research. Given that society values sentient animals and that basic research is not goal oriented, the question is raised: "Is the use of sentient animals in basic research justifiable?" We explore this in the context of funding issues, outcomes from basic research, and the position of society as a whole on using sentient animals in research that is not goal oriented. We conclude that the use of sentient animals in basic research cannot be justified in light of society's priorities. © 2010 Greek and Jean; licensee BioMed Central Ltd.
引用
收藏
相关论文
共 134 条
[81]  
Smith R., Comroe and Dripps revisited, Br Med J (Clin Res Ed), 295, pp. 1404-1407, (1987)
[82]  
Farrar S., Key basic research study proves fatally ambiguous, The Times Higher Education, (2003)
[83]  
Grant J., Green L., Mason B., Basic research and health: a reassessment of the scientific basis for the support of biomedical science, Research Evaluation, 12, pp. 217-224, (2003)
[84]  
Contopoulos-Ioannidis D.G., Ntzani E., Ioannidis J.P., Translation of highly promising basic science research into clinical applications, Am J Med, 114, pp. 477-484, (2003)
[85]  
Lost in clinical translation, Nat Med, 10, (2004)
[86]  
Crowley W.F., Translation of basic research into useful treatments: how often does it occur?, Am J Med, 114, pp. 503-505, (2003)
[87]  
Hamilton D.P., Publishing by--and for?--the numbers, Science, 250, pp. 1331-1332, (1990)
[88]  
Steinman R., Szalavitz M., Patients Have Been Too Patient With Basic Research, Cerebrum, 4, (2002)
[89]  
Ioannidis J.P., Materializing research promises: opportunities, priorities and conflicts in translational medicine, J Transl Med, 2, (2004)
[90]  
Grant J., Cottrell R., Cluzeau F., Fawcett G., Evaluating "payback" on biomedical research from papers cited in clinical guidelines: applied bibliometric study, BMJ, 320, pp. 1107-1111, (2000)