Quality assurance in intensive care medicine. SARI - Surveillance on antibiotic use and bacterial resistance in intensive care units

被引：2
作者：
Meyer E. [1 ,6 ]
Schroeren-Boersch B. [1 ]
Schwab F. [2 ,3 ,5 ]
Jonas D. [1 ]
Rüden H. [2 ,3 ,5 ]
Gastmeier P. [4 ,5 ]
Daschner F.D. [1 ,5 ]
机构：
[1] Inst. Umweltmedizin K., Universitätsklinikum Freiburg
[2] Institut für Hygiene, Univ. Klin. Benjamin Franklin, Freie Universität Berlin
[3] Zentralbereich Krankenhaushygiene I., Univ. Klin. Charité, Humboldt-Universität Berlin
[4] Inst. Med. Mikrobiol. K., Medizinische Hochschule Hannover
[5] Inst. Umweltmedizin K., Universitätsklinikum Freiburg, 79106 Freiburg
来源：
Der Anaesthesist | 2004年 / 53卷 / 5期
关键词：
Antibiotic use; Intensive care units; Resistance rates; SARI; Surveillance;
D O I：
10.1007/s00101-004-0668-2
中图分类号：
学科分类号：
摘要：
Intensive care units (ICUs) are high risk areas for emergence and spread of multiresistant bacterial pathogens. In Germany, there are no representative epidemiological data on antibiotic resistance, prophylactic or therapeutic use of antibiotics in ICUs, or on the correlation between antibiotic use and emergence of resistance. Supported by the German Ministry of Science and Education, project SARI (Surveillance on antibiotic use and bacterial resistance in ICUs) started in 02/2000 and now includes data on antibiotic use and resistance rates in 35 medical, surgical and interdisciplinary ICUs. To date (2/2000-12/2002), a total of 939 participant months, 339,461 patient days and 452,282 defined daily doses (DDD) have been covered with a mean antibiotic usage density (AD) of 1,332 DDDs/1,000 patient days and resistance data on 31,189 isolates from ICUs. The design of the project and first results of SARI are presented. The epidemiological data of SARI form a basis for improved antibiotic and infection control management in ICUs (http://www.sari-antibiotika.de).
引用
收藏
页码：427 / 433
页数：6
相关论文
共 9 条
  • [1] Archibald L., Phillips L., Monnet D., McGowan Jr. J.E., Tenover F., Gaynes R., Antimicrobial resistance in isolates from inpatients and outpatients in the United States: Increasing importance of the intensive care unit, Clin Infect Dis, 24, pp. 211-215, (1997)
  • [2] Fridkin S.K., Steward C.D., Edwards J.R., Et al., Surveillance of antimicrobial use and antimicrobial resistance in United States hospitals: Project ICARE phase 2, Clin Infect Dis, 29, pp. 245-252, (1999)
  • [3] Geffers C., Koch J., Sohr D., Nassauer A., Daschner F., Ruden H., Gastmeier P., Aufbau einer Referenzdatenbank für nosokomiale Infektionen auf Intensivstationen. Erste Ergebnisse des nationalen Krankenhaus-Infektions- Surveillance-Systems (KISS), Anästhesist, 49, pp. 732-737, (2000)
  • [4] Kresken M., Hafner D., Resistenzsituation bei klinisch wichtigen Infektionserregern gegenüber Chemotherapeutika in Mitteleuropa, Chemother J, 9, pp. 51-86, (2000)
  • [5] Kresken M., Hafner D., Schmitz F., Wichelhaus T., Resistenzsituation bei klinisch wichtigen Infektionserregern gegenüber Antibiotika in Deutschland und im mitteleuropäischen Raum, PEG-Resistenzstudie, pp. 1-86, (2003)
  • [6] Meyer E., Jonas D., Schwab F., Rueden H., Gastmeier P., Daschner F.D., Design of a surveillance system of antibiotic use and bacterial resistance in German intensive care units (SARI), Infection, 31, pp. 93-100, (2003)
  • [7] Monnet D.L., Sorensen T.L., Interpreting the effectiveness of a national antibiotic policy and comparing antimicrobial use between countries, J Hosp Infect, 43, pp. 239-242, (1999)
  • [8] Monnet D.L., Archibald L.K., Phillips L., Tenover F.C., McGowan Jr. J.E., Gaynes R.P., Antimicrobial use and resistance in eight US hospitals: Complexities of analysis and modeling, Infect Control Hosp Epidemiol, 19, pp. 388-394, (1998)
  • [9] National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 to June 2002, Am J Infect Control, 30, pp. 458-475, (2002)
1