Fluorescence of a Benzothienopyridopyrimidone in Solution and in Lipid Vesicles

被引：0
|
作者：
Elisabete M. S. Castanheira
Ana M. R. Pinto
Maria-João R. P. Queiroz
机构：
[1] Universidade do Minho,Departamento de Física
[2] Universidade do Minho,Departamento de Química
来源：
Journal of Fluorescence | 2006年 / 16卷
关键词：
Benzothienopyridopyrimidone; pH probe; Lipid vesicles;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Fluorescence properties of a biologically active benzothienopyridopyrimidone in solution and in lipid vesicles are reported. Assays at different pH values (0.5–10) allowed the determination of pKa = 2.0, showing that this compound may be useful as a pH indicator for pH ≤ 4. In lipid vesicles, benzothienopyridopyrimidone locates in a water-rich environment, indicating that it can be carried in the hydrophilic region of liposomes for drug delivery applications.
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页码：251 / 257
页数：6
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