Investigating T-cell memory

被引：0

作者：

Alberto Mantovani

机构：

[1] Istituto di Ricerche Farmacologiche ‘Mario Negri’,Department of Biotechnology

[2] Section of General Pathology University of Brescia,undefined

来源：

Nature | 2000年 / 407卷

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D O I：

暂无

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摘要：

Memory is a long-recognized, crucial and poorly understood property of adaptive immunity. Jacob and Baltimore1 have designed an elegant genetic approach to marking memory T cells and their precursors irreversibly and have obtained intriguing results1,2. I suggest that the particular enzyme (human placental alkaline phosphatase) chosen for irreversible marking in postnatal life contributes to certain features of this system and perturbs the homeostatic mechanisms of T-cell activation and death.

引用

页码：40 / 40

共 50 条

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