High-throughput N-glycan screening method for therapeutic antibodies using a microchip-based DNA analyzer: a promising methodology for monitoring monoclonal antibody N-glycosylation

被引：0
|
作者：
Mitsuhiro Kinoshita
Kazuki Nakajima
Sachio Yamamoto
Shigeo Suzuki
机构：
[1] Kindai University,Department of Pharmaceutical Sciences
[2] Fujita Health University,Center for Joint Research Facilities Support, Research Promotion and Support Headquarters
来源：
Analytical and Bioanalytical Chemistry | 2021年 / 413卷
关键词：
-glycosylation; Therapeutic antibodies; Microchip electrophoresis; High-throughput methodology;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：4727 / 4738
页数：11
相关论文
共 9 条
  • [1] High-throughput N-glycan screening method for therapeutic antibodies using a microchip-based DNA analyzer: a promising methodology for monitoring monoclonal antibody N-glycosylation
    Kinoshita, Mitsuhiro
    Nakajima, Kazuki
    Yamamoto, Sachio
    Suzuki, Shigeo
    ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2021, 413 (19) : 4727 - 4738
  • [2] Ultrafast and high-throughput N-glycan analysis for monoclonal antibodies
    Yang, Xiaoyu
    Kim, Sunnie Myung
    Ruzanski, Richard
    Chen, Yuetian
    Moses, Sarath
    Ling, Wai Lam
    Li, Xiaojuan
    Wang, Shao-Chun
    Li, Huijuan
    Ambrogelly, Alexandre
    Richardson, Daisy
    Shameem, Mohammed
    MABS, 2016, 8 (04) : 706 - 717
  • [3] A high-throughput microchip-based glycan screening assay for antibody cell culture samples
    Primack, Jeremy
    Flynn, Gregory C.
    Pan, Hai
    ELECTROPHORESIS, 2011, 32 (10) : 1129 - 1132
  • [4] High-throughput quantitative analysis of plant N-glycan using a DNA sequencer
    Lee, Kyung Jin
    Jung, Jin-Hee
    Lee, Jung Mi
    So, Yangkang
    Kwon, Ohsuk
    Callewaert, Nico
    Kang, Hyun Ah
    Ko, Kisung
    Oh, Doo-Byoung
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 380 (02) : 223 - 229
  • [5] High throughput human plasma N-glycan analysis using DNA analyzer and multivariate analysis for biomarker discovery
    Feng, Hua-tao
    Lim, Siying
    Laserna, Anna Karen Carrasco
    Li, Pingjing
    Yin, Xuejiao
    Simsek, Erhan
    Khan, Shaheer H.
    Chen, Shiaw-Min
    Li, Sam F. Y.
    ANALYTICA CHIMICA ACTA, 2017, 995 : 106 - 113
  • [6] Rapid Magnetic Bead Based Sample Preparation for Automated and High Throughput N-Glycan Analysis of Therapeutic Antibodies
    Varadi, Csaba
    Lew, Clarence
    Guttman, Andras
    ANALYTICAL CHEMISTRY, 2014, 86 (12) : 5682 - 5687
  • [7] Hydrophilic interaction chromatography-based high-throughput sample preparation method for N-glycan analysis from total human plasma glycoproteins
    Ruhaak, L. Renee
    Huhn, Carolin
    Waterreus, Willem-Jan
    de Boer, Arjen R.
    Neusuess, Christian
    Hokke, Cornelis H.
    Deelder, Andre M.
    Wuhrer, Manfred
    ANALYTICAL CHEMISTRY, 2008, 80 (15) : 6119 - 6126
  • [8] Semi-high-throughput isolation and N-glycan analysis of human fibrinogen using monolithic supports bearing monoclonal anti-human fibrinogen antibodies
    Vidic, Urska
    Trbojevic-Akmacic, Irena
    Cernigoj, Urh
    Albers, Malena
    Gaspersic, Jernej
    Pucic-Bakovic, Maja
    Vidic, Jana
    Strancar, Ales
    Lauc, Gordan
    ELECTROPHORESIS, 2017, 38 (22-23) : 2922 - 2930
  • [9] High-Throughput Method Development for Sensitive, Accurate, and Reproducible Quantification of Therapeutic Monoclonal Antibodies in Tissues Using Orthogonal Array Optimization and Nano Liquid Chromatography/Selected Reaction Monitoring Mass Spectrometry
    Duan, Xiaotao
    Abuqayyas, Lubna
    Dai, Lipeng
    Balthasar, Joseph P.
    Qu, Jun
    ANALYTICAL CHEMISTRY, 2012, 84 (10) : 4373 - 4382
1