Alternative splicing of interleukin-6 mRNA in mice

被引:0
作者
O. P. Yatsenko
M. L. Filipenko
E. A. Khrapov
E. N. Voronina
S. V. Sennikov
V. A. Kozlov
机构
[1] Siberian Division of the Russian Academy of Medical Sciences,Laboratory for Regulation of Immunopoiesis, Institute of Clinical Immunology
[2] Siberian Division of the Russian Academy of Sciences,Institute of Bioorganic Chemistry
来源
Bulletin of Experimental Biology and Medicine | 2004年 / 138卷
关键词
interleukin-6; alternative splicing;
D O I
暂无
中图分类号
学科分类号
摘要
Expression of mRNA for interleukin-6, interleukin-6Δ3, and interleukin-6Δ5 was detected in placental tissue (second and third trimesters of pregnancy) and spleen of mice immunized with sheep erythrocytes in high dose. We hypothesize that translation of mRNA yields proteins capable of binding to individual subunits of the interleukin-6 receptor and possessing effector functions.
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页码:73 / 76
页数:3
相关论文
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