QSAR STUDIES ON ADENOSINE KINASE INHIBITORS

被引:0
作者
Vijay K. Agrawal
Kamana Singh
Padmakar V. Khadikar
机构
[1] A.P.S. University,QSAR and Computer Chemical Laboratories
[2] Laxmi Fumigation and Pest Control Pvt. Ltd.,Research Division
来源
Medicinal Chemistry Research | 2004年 / 13卷
关键词
Regression Analysis; Adenosine; Pyrimidine; Kinase Inhibitor; Nucleoside;
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摘要
The present study reports QSAR study on adenosine kinase inhibitors pyrrolo[2, 3-d] pyrimidine nucleoside analogous. The equalized electronegativity along with a large pool of topological indices are used for the purpose. The regression analysis has shown that equalized electronegativity is a good parameter which in combination with topological indices and an indicator parameter gave excellent model.
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页码:479 / 496
页数:17
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