Impact of a 4-year antimicrobial stewardship program implemented in a Greek tertiary hospital

被引：0

作者：

Konstantina Chrysou

Olympia Zarkotou

Sofia Kalofolia

Panagiota Papagiannakopoulou

Vasiliki Mamali

Georgios Chrysos

Katina Themeli-Digalaki

Nikolaos Sypsas

Athanasios Tsakris

Spyros Pournaras

机构：

[1] National and Kapodistrian University of Athens,Department of Microbiology

[2] Tzaneio General Hospital of Piraeus,Department of Clinical Microbiology

[3] Tzaneio General Hospital of Piraeus,Hospital Pharmacy

[4] Tzaneio General Hospital of Piraeus,2nd Department of Medicine and Infectious Disease Unit

[5] National and Kapodistrian University of Athens,General Hospital of Athens “Laiko”

[6] National and Kapodistrian University of Athens,Laboratory of Clinical Microbiology, ATTIKON University Hospital

来源：

European Journal of Clinical Microbiology & Infectious Diseases | 2022年 / 41卷

关键词：

Antibiotic consumption; Antimicrobial stewardship; infections; Antibiotic costs; Length of hospital stay;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

This study aimed to investigate the effects of a 4-year antibiotic stewardship program (ASP) in a tertiary hospital. We monitored data for 2015 (pre-intervention) and 2016–2019 (post-intervention) about antibiotic consumption (DDD/100 bed days), Clostridioides difficile infections (CDIs), resistance rates, length of stay (LOS), and annual antibiotic costs. Significant reductions were observed for total antibiotics/colistin/carbapenems/quinolones/tigecycline consumption and resistance rates of Pseudomonas aeruginosa, Klebsiella pneumoniae, and vancomycin-resistant enterococci. Considerable reductions occurred for LOS (4.18 [2015]/3.0 [2019] days), CDIs (1.47 [2015]/0.86 [2019] per 1000 patients), antibiotic cost/patient (39.45€ [2015]/23.69€ [2019]). The ASP was successful in reducing antibiotic consumption, antibiotic costs, length of hospital stay, and CDIs.

引用

页码：127 / 132

页数：5

共 57 条

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