Long noncoding RNA SNHG17: a novel molecule in human cancers

被引：0
作者：
Li Ma
Jin Gao
Niu Zhang
Jiawei Wang
Tianwei Xu
Tianyao Lei
Xiaoteng Zou
Chenchen Wei
Zhaoxia Wang
机构：
[1] The Second Affiliated Hospital of Nanjing Medical University,Cancer Medical Center
[2] The Second Affiliated Hospital of Nanjing Medical University,Department of General Surgery
来源：
Cancer Cell International | / 22卷
关键词：
SNHG17; lncRNA; Cancer; Gene regulation; Diagnosis; Prognosis;
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摘要：
Many studies in recent years have found that dysregulation of long non-coding RNAs (lncRNAs) can contribute to disease. Small nucleolar RNA host gene 17 (SNHG17) is a novel cancer-related lncRNA of the SNHG family which is highly expressed in various tumors and may exert oncogenic functions. Several studies have demonstrated that SNHG17 is closely related to the proliferation, migration, invasion, apoptosis, and chemical drug resistance of tumor cells, and clinical studies have found an association between high SNHG17 expression and poor prognosis. In this review, we summarize relevant studies investigating SNHG17, focusing on its biological function as well as its potential value for clinical applications.
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