A concise and simple synthesis of 1-hydroxy-phenethylamine derivatives: Formal synthesis of naturally occurring norephedrine, virolin and 3-hydroxy-2-phosphonylmethoxypropyl adenine

被引:0
作者
S SAHA
P CHAKRABORTY
S C ROY
机构
[1] Indian Association for the Cultivation of Science,Department of Organic Chemistry
[2] National Institute of Technology,Department of Chemistry
来源
Journal of Chemical Sciences | 2014年 / 126卷
关键词
Synthesis; 1-hydroxy-phenethylamine derivatives; intermediates; bio-active; small molecules;
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学科分类号
摘要
A concise and simple synthesis of 1-hydroxy-phenethylamine derivatives has been achieved following classical organic transformations using commercially available chiral pools. The said derivatives were explored for the synthesis of naturally occurring bio-active small molecules. Formal synthesis of norephedrine, virolin and 3-hydroxy-2-phosphonylmethoxypropyl adenine has been demonstrated.
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页码:837 / 846
页数:9
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