Efficacy and Safety of Nebulized Formoterol as Add-on Therapy in COPD Patients Receiving Maintenance Tiotropium BromideResults from a 6-Week, Randomized, Placebo-Controlled, Clinical Trial

被引：0
作者：
Nicola A. Hanania
Ahmad Boota
Edward Kerwin
LaTanya Tomlinson
Kimberly Denis-Mize
机构：
[1] Baylor College of Medicine,
[2] Greenville Pharmaceutical Research,undefined
[3] Clinical Research Institute of Southern Oregon,undefined
[4] PC,undefined
[5] Formerly of Dey L.P,undefined
[6] Dey,undefined
[7] L.P.,undefined
来源：
Drugs | 2009年 / 69卷
关键词：
Chronic Obstructive Pulmonary Disease; Formoterol; Tiotropium; Tiotropium Bromide; Inspiratory Capacity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background: Current guidelines for the treatment of chronic obstructive pulmonary disease (COPD) recommend the use of long-acting bronchodilators in the maintenance management of COPD. Combining bronchodilators that work through different mechanisms is recommended in patients with continuous symptoms.
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收藏
页码：1205 / 1216
页数：11
相关论文
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[1]  
Anderson GP(1994)Why are long-acting beta-adrenoceptor agonists long-acting Eur Respir J 7 569-78
[2]  
Linden A(2007)Is combination therapy with inhaled anticholinergics and beta2-adrenoceptor agonists justified for chronic obstructive pulmonary disease Drugs Aging 24 615-28
[3]  
Rabe KF(2003)Long-acting beta 2-adrenoceptor agonists or tiotropium bromide for patients with COPD: is combination therapy justified Curr Opin Pharmacol 3 270-6
[4]  
Reddy CB(2004)Tiotropium bromide: a review of its use as maintenance therapy in patients with COPD Treat Respir Med 3 247-68
[5]  
Kanner RE(1994)Effect of Ba 679 BR, a novel long-acting anticholinergic agent, on cholinergic neurotransmission in guinea pig and human airways Am J Respir Crit Care Med 150 1640-5
[6]  
Tennant RC(2006)Onset and duration of action of formoterol and tiotropium in patients with moderate to severe COPD Respiration 73 414-9
[7]  
Erin EM(2002)Effects of salmeterol on mucosal inflammation in asthma: a placebo-controlled study Eur Respir J 20 1378-85
[8]  
Barnes PJ(2001)Alternative mechanisms for long-acting beta (2)-adrenergic agonists in COPD Chest 120 258-70
[9]  
Keam SJ(2007)Doppler echocardiographic assessment of the effects of inhaled long-acting β Pulmon Pharmacol Ther 20 258-64
[10]  
Keating GM(2004)-agonists on pulmonary artery pressure in COPD patients Chest 125 249-59
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