Osmophobia in primary headaches

被引:32
作者
Zanchin G. [1 ]
Dainese F. [1 ]
Mainardi F. [1 ]
Mampreso E. [1 ]
Perin C. [1 ]
Maggioni F. [1 ]
机构
[1] Headache Centre, Department of Neurosciences, University of Padua, Padua
关键词
International Headache Classification; Migraine; Osmophobia; Primary headaches;
D O I
10.1007/s10194-005-0188-8
中图分类号
学科分类号
摘要
This study evaluates osmophobia (defined as an unpleasant perception, during a headache attack, of odours that are non-aversive or even pleasurable outside the attacks) in connection with the diagnosis of primary headaches. We recruited 775 patients from our Headache Centre (566 females, 209 males; age 38±12 years), of whom 477 were migraineurs without aura (MO), 92 with aura (MA), 135 had episodic tension-type headache (ETTH), 44 episodic cluster headache (ECH), 2 chronic paroxysmal hemicrania (CPH) and 25 other primary headaches (OPHs: 12 primary stabbing headaches, 2 primary cough headaches, 3 primary exertional headaches, 2 primary headaches associated with sexual activity, 3 hypnic headaches, 2 primary thunderclap headaches and 1 hemicrania continua). Among them, 43% with MO (205/477), 39% with MA (36/92), and 7% with CH (3/44) reported osmophobia during the attacks; none of the 135 ETTH and 25 OPH patients suffered this symptom. We conclude that osmophobia is a very specific marker to discriminate adequately between migraine (MO and MA) and ETTH; moreover, from this limited series it seems to be a good discriminant also for OPHs, and for CH patients not sharing neurovegetative symptoms with migraine. Therefore, osmophobia should be considered a good candidate as a new criterion for the diagnosis of migraine. © Springer-Verlag Italia 2005.
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页码:213 / 215
页数:2
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