Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection

被引：0
|
作者：
Benjamin Petsch
Margit Schnee
Annette B Vogel
Elke Lange
Bernd Hoffmann
Daniel Voss
Thomas Schlake
Andreas Thess
Karl-Josef Kallen
Lothar Stitz
Thomas Kramps
机构：
[1] Institute of Immunology,
[2] Friedrich-Loeffler-Institut,undefined
[3] CureVac GmbH,undefined
[4] Department of Experimental Animal Facilities and Biorisk Management,undefined
[5] Institute of Diagnostic Virology,undefined
[6] Friedrich-Loeffler-Institut,undefined
[7] Current addresses: CureVac GmbH,undefined
[8] Tübingen,undefined
[9] Germany (B.P.); Institute of Immunology,undefined
[10] Friedrich-Loeffler-Institut,undefined
[11] Greifswald-Insel Riems,undefined
[12] Germany (A.B.V. and L.S.).,undefined
来源：
Nature Biotechnology | 2012年 / 30卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Petsch et al. apply mRNA vaccination for the first time to infectious disease, demonstrating immunogenicity and/or protective effects against influenza virus in mice, ferrets and pigs.
引用
收藏
页码：1210 / 1216
页数：6
相关论文
共 50 条
  • [1] Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection
    Petsch, Benjamin
    Schnee, Margit
    Vogel, Annette B.
    Lange, Elke
    Hoffmann, Bernd
    Voss, Daniel
    Schlake, Thomas
    Thess, Andreas
    Kallen, Karl-Josef
    Stitz, Lothar
    Kramps, Thomas
    NATURE BIOTECHNOLOGY, 2012, 30 (12) : 1210 - +
  • [2] Protective efficacy of DNA vaccines against duck hepatitis B virus infection
    Triyatni, M
    Jilbert, AR
    Qiao, M
    Miller, DS
    Burrell, CJ
    JOURNAL OF VIROLOGY, 1998, 72 (01) : 84 - 94
  • [3] EFFICACY OF INFLUENZA HEMAGGLUTININ AND NUCLEOPROTEIN AS PROTECTIVE ANTIGENS AGAINST INFLUENZA-VIRUS INFECTION IN MICE
    ANDREW, ME
    COUPAR, BEH
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 1988, 28 (01) : 81 - 85
  • [4] Humice to test efficacy of vaccines against influenza virus
    Yu, Chun I.
    Marches, Florentina
    Gallegos, Mike
    Garcia-Sastre, Adolfo
    Banchereau, Jacques
    Palucka, A. Karolina
    JOURNAL OF IMMUNOLOGY, 2006, 176 : S103 - S103
  • [5] mRNA encoding antibodies against hemagglutinin and nucleoprotein prevents influenza virus infection in vitro
    Zabrodskaya, Y. A.
    Gavrilova, N. V.
    Elpaeva, E. A.
    Lozhkov, A. A.
    Vysochinskaya, V. V.
    Dobrovolskaya, O. A.
    Dovbysh, O. V.
    Zimmerman, E. L.
    Dav, P. N.
    Brodskaia, A. V.
    Sakhenberg, E. I.
    Shaldzhyan, A. A.
    Demaev, A. A.
    Maslov, M. A.
    Vasin, A. V.
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 738
  • [6] Polymeric nanoparticle-based mRNA vaccine is protective against influenza virus infection in ferrets
    Hardenberg, Gijs
    Brouwer, Chantal
    van Gemerden, Rachelle
    Jones, Nicola J.
    Marriott, Anthony C.
    Rip, Jaap
    MOLECULAR THERAPY NUCLEIC ACIDS, 2024, 35 (01):
  • [7] DEVELOPMENT OF IMMUNITY AGAINST INFLUENZA-A VIRUS-INFECTION IN CHILDHOOD BY CONVENTIONAL AND NEURAMINIDASE SPECIFIC INFLUENZA VACCINES
    CHOW, T
    BEUTNER, KR
    CLEMENT, J
    OGRA, PL
    PEDIATRIC RESEARCH, 1978, 12 (04) : 490 - 490
  • [8] Modified mRNA Vaccines Protect against Zika Virus Infection
    Richner, Justin M.
    Himansu, Sunny
    Dowd, Kimberly A.
    Butler, Scott L.
    Salazar, Vanessa
    Fox, Julie M.
    Julander, Justin G.
    Tang, William W.
    Shresta, Sujan
    Pierson, Theodore C.
    Ciaramella, Giuseppe
    Diamond, Michael S.
    CELL, 2017, 168 (06) : 1114 - +
  • [9] EFFICACY OF VACCINES AGAINST INFLUENZA
    SHAPIRO, BG
    SOUTH AFRICAN MEDICAL JOURNAL, 1974, 48 (48): : 2009 - 2009
  • [10] Host Protective Immune Responses against Influenza A Virus Infection
    Jung, Hi Eun
    Lee, Heung Kyu
    VIRUSES-BASEL, 2020, 12 (05):
12345