Rhein alleviates renal interstitial fibrosis by inhibiting tubular cell apoptosis in rats

[1] Neilson EG(2006)Mechanisms of disease: fibroblasts—a new look at an old problem Nat Clin Pract Nephrol 2 101-108

[2] Wynn TA(2008)Cellular and molecular mechanisms of fibrosis J Pathol 214 199-210

[3] Liu Y(2004)Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention J Am Soc Nephrol 15 1-12

[4] Miyajima A(2000)Antibody to transforming growth factor-beta ameliorates tubular apoptosis in unilateral ureteral obstruction Kidney Int 58 2301-2313

[5] Chen J(2009)Fibroblast activation and myofibroblast generation in obstructive nephropathy Nat Rev Nephrol 5 319-328

[6] Lawrence C(2007)Signal transducer and activator of transcription 3 involvement in the development of renal interstitial fibrosis after unilateral ureteral obstruction Nephrology (Carlton) 12 565-571

[7] Ledbetter S(2006)STAT3 attenuates EGFR-mediated ERK activation and cell survival during oxidant stress in mouse proximal tubular cells Kidney Int 70 669-674

[8] Soslow RA(2008)Blockage of JAK/STAT signalling attenuates renal ischaemia-reperfusion injury in rat Nephrol Dial Transpl 23 91-100

[9] Stern J(2008)STAT3: an important regulator of multiple cytokine functions Transplantation 85 1372-1377

[10] Grande MT(2000)STAT proteins: novel molecular targets for cancer drug discovery Oncogene 19 6613-6626

[1] Neilson EG(2006)Mechanisms of disease: fibroblasts—a new look at an old problem Nat Clin Pract Nephrol 2 101-108

[2] Wynn TA(2008)Cellular and molecular mechanisms of fibrosis J Pathol 214 199-210

[3] Liu Y(2004)Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention J Am Soc Nephrol 15 1-12

[4] Miyajima A(2000)Antibody to transforming growth factor-beta ameliorates tubular apoptosis in unilateral ureteral obstruction Kidney Int 58 2301-2313

[5] Chen J(2009)Fibroblast activation and myofibroblast generation in obstructive nephropathy Nat Rev Nephrol 5 319-328

[6] Lawrence C(2007)Signal transducer and activator of transcription 3 involvement in the development of renal interstitial fibrosis after unilateral ureteral obstruction Nephrology (Carlton) 12 565-571

[7] Ledbetter S(2006)STAT3 attenuates EGFR-mediated ERK activation and cell survival during oxidant stress in mouse proximal tubular cells Kidney Int 70 669-674

[8] Soslow RA(2008)Blockage of JAK/STAT signalling attenuates renal ischaemia-reperfusion injury in rat Nephrol Dial Transpl 23 91-100

[9] Stern J(2008)STAT3: an important regulator of multiple cytokine functions Transplantation 85 1372-1377

[10] Grande MT(2000)STAT proteins: novel molecular targets for cancer drug discovery Oncogene 19 6613-6626