Renal cell carcinoma: Recent developments in diagnostics and therapy

被引：3

作者：

Bedke J. ^{[1
]}

Stenzl A. ^{[1
]}

机构：

[1] Klinik für Urologie, Eberhard Karls Universität Tübingen, 72076 Tübingen

来源：

Der Urologe | 2010年 / 49卷 / Suppl 1期

关键词：

Adjuvant therapy; Diagnostic techniques; surgical; Nephrectomy; Renal cell carcinoma; Targeted therapy;

D O I：

10.1007/s00120-010-2378-5

中图分类号：

学科分类号：

摘要：

This review highlights new strategies in the treatment of renal cell carcinoma (RCC). The benign or malignant status of renal masses in preoperative imaging as well as the detection of metastases and their differentiation from secondary malignancies is discussed. For the prognostic stratification of RCC the TNM system has been adopted. Nephron-sparing (NS) techniques of laparoscopy, radiofrequency and cryoablation are critically compared and the newest results of robotic-assisted (DaVinci) NS surgery are given. The special question of cytoreductive surgery in primary metastatic disease and the question of adjuvant immunotherapy are raised. New medical treatment strategies including new substances, vaccines and the possibility of sequential therapy are discussed. © 2010 Springer-Verlag.

引用

页码：178 / 184

页数：6

共 41 条

[11]

Flanigan R.C., Mickisch G., Sylvester R., Et al., Cytoreductive nephrectomy in patients with metastatic renal cancer: A combined analysis, J Urol, 171, pp. 1071-1076, (2004)

[12]

Flanigan R.C., Salmon S.E., Blumenstein B.A., Et al., Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer, N Engl J Med, 345, pp. 1655-1659, (2001)

[13]

Gakis G., Kramer U., Schilling D., Et al., Small renal oncocytomas: Differentiation with multiphase CT, Eur J Radiol, 2010

[14]

Gupta K., Miller J.D., Li J.Z., Et al., Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): A literature review, Cancer Treat Rev, 34, pp. 193-205, (2008)

[15]

Herrmann E., Bierer S., Wulfing C., Update on systemic therapies of metastatic renal cell carcinoma, World J Urol, 28, pp. 303-309, (2010)

[16]

Jocham D., Richter A., Hoffmann L., Et al., Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal-cell carcinoma after radical nephrectomy: Phase III, randomised controlled trial, Lancet, 363, pp. 594-599, (2004)

[17]

Jung D.C., Choi H.J., Kim H.Y., Et al., Pulmonary metastasis from renal cell carcinoma: Characterization using contrast-enhanced CT attenuation value measurements, J Comput Assist Tomogr, 33, pp. 54-57, (2009)

[18]

Kaouk J.H., Goel R.K., Single-port laparoscopic and robotic partial nephrectomy, Eur Urol, 55, pp. 1163-1169, (2009)

[19]

Klatte T., Patard J.J., Goel R.H., Et al., Prognostic impact of tumor size on pT2 renal cell carcinoma: An international multicenter experience, J Urol, 178, pp. 35-40, (2007)

[20]

Kowalczyk K.J., Hooper H.B., Linehan W.M., Et al., Partial nephrectomy after previous radio frequency ablation: The National Cancer Institute experience, J Urol, 182, pp. 2158-2163, (2009)

← 1 2 3 4 5 →