A Comparative Review of Methods for T Cell Depletion in the Prophylaxis of Graft-versus-Host Disease

被引：0
作者：
Bernd Hertenstein
Lubomir Arseniev
Jürgen Novotny
Arnold Ganser
机构：
[1] Hannover Medical School,Department of Hematology and Oncology
来源：
BioDrugs | 1998年 / 9卷
关键词：
Adis International Limited; Chronic Myeloid Leukemia; Graft Failure; Acute GVHD; Cell Depletion;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Graft-versus-host disease (GVHD) remains the major problem to be overcome in transplantation of allogeneic haemopoietic stem cells. Using immunosuppressive prophylaxis with cyclosporin and methotrexate, moderate to severe acute GVHD develops in approximately 45% of transplant recipients with an HLA-identical sibling donor and in >75% of patients from unrelated HLA-identical or partially matched related donors.
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页码：105 / 123
页数：18
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