Trichomoniasis: What's new?

被引：6

作者：

Karen A. Wendel

机构：

[1] Division of Infectious Diseases, Oklahoma Univ. Health Science Center, Oklahoma City, OK 73104

来源：

Current Infectious Disease Reports | 2003年 / 5卷 / 2期

关键词：

Metronidazole; Bacterial Vaginosis; Urethritis; Tinidazole; Trichomoniasis;

D O I：

10.1007/s11908-003-0049-z

中图分类号：

学科分类号：

摘要：

Trichomonas vaginalis is the most common nonviral sexually transmitted disease in the world. Recent research has elucidated several virulence factors that allow T. vaginalis to adhere to extracellular host proteins and evade the host immune system. Further investigation is needed to determine the mechanisms responsible for the perinatal morbidity associated with trichomoniasis and to evaluate the interactions between trichomoniasis and HIV infection. An effort to decrease T. vaginalis associated with perinatal morbidity by metronidazole treatment in pregnancy was unsuccessful. However, more sensitive tools for diagnosis such as polymerase chain reaction may further facilitate future understanding of the epidemiology and risk factors of disease and improve approaches to control this widespread infection. Treatment has remained highly efficacious with single-dose metronidazole, although concern regarding drug resistance has led to more systematic evaluations of the prevalence of metronidazole resistance and alternatives to metronidazole treatment. Copyright © 2003 by Current Science Inc.

引用

页码：129 / 134

页数：5

共 55 条

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