Chondroblastic osteosarcoma: characterisation by gadolinium-enhanced MR imaging correlated with histopathology

被引：0

作者：

M. J. A. Geirnaerdt

Johan L. Bloem

Henk-Jan van der Woude

Anthonie H. M. Taminiau

Marianne A. Nooy

Pancras C. W. Hogendoorn

机构：

[1] Department of Radiology,

[2] C2S,undefined

[3] Leiden University Medical Center,undefined

[4] Albinusdreef 2,undefined

[5] PO Box 9600,undefined

[6] 2300 RC Leiden,undefined

[7] The Netherlands,undefined

[8] Department of Orthopedic Surgery,undefined

[9] Leiden University Medical Center,undefined

[10] Leiden,undefined

[11] The Netherlands,undefined

[12] Department of Clinical Oncology,undefined

[13] Leiden University Medical Center,undefined

[14] Leiden,undefined

[15] The Netherlands,undefined

[16] Department of Pathology,undefined

[17] Leiden University Medical Center,undefined

[18] Leiden,undefined

[19] The Netherlands,undefined

来源：

Skeletal Radiology | 1998年 / 27卷

关键词：

Key words Osteosarcoma; Sarcoma; Cartilage; Bone neoplasms; MRI; Gadolinium;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Objective. To identify specific features of chondroblastic osteosarcoma on gadopentetate dimeglumine (Gd)-enhanced magnetic resonance (MR) imaging. Design and patients. Nine patients with chondroblastic osteosarcoma and a control group of 20 patients with conventional central osteosarcoma were included in this study. The histopathological findings of the surgical specimens were compared with enhancement patterns on static Gd-enhanced MR images. Results. In chondroblastic osteosarcoma septonodular and peripheral rim enhancement represented tumour with a pure chondroid matrix. Non-enhancing and heterogeneous enhancing areas represented tumour with both chondroid and osteoid matrix. In the tumours in the control group enhancement was predominantly heterogeneous but in one it was homogeneous. All these areas corresponded to necrotic or viable osteoid tumour tissue or fibrovascular tissue in areas of necrosis. Conclusion. Gd-enhanced MR imaging can assist in obtaining diagnostic biopsy material of chondroblastic osteosarcoma by identifying both osteoid- and chondroid-forming areas.

引用

页码：145 / 153

页数：8