On modelling of immune memory mechanisms

被引：1

作者：

E. Ahmed

A. H. Hashish

机构：

[1] Department of Physics, Faculty of Science, UAE University

[2] Department of Mathematics, Faculty of Science, UAE University, Al-Ain

来源：

Theory in Biosciences | 2003年 / 122卷 / 4期

关键词：

Extremal dynamics; Immune memory; Mathematical Models;

D O I：

10.1007/s12064-003-0062-7

中图分类号：

学科分类号：

摘要：

In human body, the acquired protection against illness is a biological property known as immunological memory. Different mechanisms for immunological memory are proposed and modeled. The first mechanism is the persisting antigen (Ag) where parts of the Ag are anticipated to persist on some Ag presenting cells. A novel application of the Hsu et al.’s model allows stable low Ag density equilibrium state. This state will correspond to the persisting Ag mechanism for the immune memory. The second is idiotypic and extremal mechanisms where mathematical models showed that a memory state could arise in this case. Finally, a simple model is given which shows that competition between effectors may contribute to the memory state. © 2003, Urban & Fischer Verlag.

引用

页码：339 / 342

页数：3

共 10 条

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