Effects of Epithalon on Activities Gastrointestinal Enzymes in Young and Old Rats

被引:0
作者
V. Kh. Khavinson
V. V. Malinin
N. M. Timofeeva
V. V. Egorova
A. A. Nikitina
机构
[1] Northwestern Division of the Russian Academy of Medical Sciences,St. Petersburg Institute of Bioregulation and Gerontology
[2] Russian Academy of Sciences,I. P. Pavlov Institute of Physiology
来源
Bulletin of Experimental Biology and Medicine | 2002年 / 133卷
关键词
Epithalon; peptides; digestive enzymes; gastrointestinal tract; aging;
D O I
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学科分类号
摘要
Peroral administration of Epithalon (Ala-Glu-Asp-Gly) to male and female Wistar rats aging 3 and 11 months changed activity of enzymes hydrolyzing carbohydrates, proteins, and phosphoric acid esters in various portions of the gastrointestinal tract. The most pronounced activation of enzymes was observed in 11-month-old animals. This effect diminished the differences in enzyme activities between young and old rats (compared to untreated animals). Our results indicate that Epithalon modulates activity of gastrointestinal enzymes during aging.
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页码:290 / 292
页数:2
相关论文
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