The Characterization of the Human Nasal Epithelial Cell Line RPMI 2650 Under Different Culture Conditions and Their Optimization for an Appropriate in vitro Nasal Model

[1] Audus KL(1990)The use of cultured epithelial and endothelial cells for drug transport and metabolism studies Pharm Res 7 435-51

[2] Bartel RL(2010)RPMI 2650 epithelial model and three-dimensional reconstructed human nasal mucosa as Eur J Pharm Biopharm: Off J Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik eV 74 290-7

[3] Hidalgo IJ(2009) models for nasal permeation studies Cell Tissue Res 338 283-93

[4] Borchardt RT(2005)Thymic stromal lymphopoietin enhances tight-junction barrier function of human nasal epithelial cells Methods Mol Med 107 183-206

[5] Wengst A(1998)Well-differentiated human airway epithelial cell cultures Adv Drug Deliv Rev 29 51-79

[6] Reichl S(1995) cell models to study nasal mucosal permeability and metabolism Rhinology 33 194-8

[7] Kamekura R(1996)Evaluation of the human cell line RPMI 2650 as an Pharm Res 13 978-88

[8] Kojima T(2008) nasal model J Pharm Sci 97 1165-78

[9] Koizumi J(1964)In-vitro cell culture models of the nasal epithelium: a comparative histochemical investigation of their suitability for drug transport studies Cancer 17 170-5

[10] Ogasawara N(1965)Evaluation of human nasal RPMI 2650 cells grown at an air-liquid interface as a model for nasal drug transport studies Exp Cell Res 39 190-6

[1] Audus KL(1990)The use of cultured epithelial and endothelial cells for drug transport and metabolism studies Pharm Res 7 435-51

[2] Bartel RL(2010)RPMI 2650 epithelial model and three-dimensional reconstructed human nasal mucosa as Eur J Pharm Biopharm: Off J Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik eV 74 290-7

[3] Hidalgo IJ(2009) models for nasal permeation studies Cell Tissue Res 338 283-93

[4] Borchardt RT(2005)Thymic stromal lymphopoietin enhances tight-junction barrier function of human nasal epithelial cells Methods Mol Med 107 183-206

[5] Wengst A(1998)Well-differentiated human airway epithelial cell cultures Adv Drug Deliv Rev 29 51-79

[6] Reichl S(1995) cell models to study nasal mucosal permeability and metabolism Rhinology 33 194-8

[7] Kamekura R(1996)Evaluation of the human cell line RPMI 2650 as an Pharm Res 13 978-88

[8] Kojima T(2008) nasal model J Pharm Sci 97 1165-78

[9] Koizumi J(1964)In-vitro cell culture models of the nasal epithelium: a comparative histochemical investigation of their suitability for drug transport studies Cancer 17 170-5

[10] Ogasawara N(1965)Evaluation of human nasal RPMI 2650 cells grown at an air-liquid interface as a model for nasal drug transport studies Exp Cell Res 39 190-6