Interactions of New bis-Ammonium Thiacalix[4]arene Derivatives in 1,3-Alternate Stereoisomeric Form with Bovine Serum Albumin

被引：12
|
作者：
Burilov V. [1 ]
Mironova D.A. [1 ]
Ibragimova R.R. [1 ]
Solovieva S.E. [1 ]
Antipin I.S. [1 ]
机构：
[1] Kazan Federal University, 18 Kremlevskaya st, Kazan
来源：
BioNanoScience | 2016年 / 6卷 / 4期
基金：
俄罗斯科学基金会;
关键词：
Ammonium compounds; BSA; Luminescence; Quenching of luminescence; Thiacalix[4]arene; Triazoles;
D O I：
10.1007/s12668-016-0255-4
中图分类号：
学科分类号：
摘要：
New bis-ammonium thiacalix[4]arene derivatives with different lipophilicity were synthesized using copper(I)-catalyzed azide-alkyne cycloaddition in good yields. Binding of a new thiacalix[4]arene derivatives with bovine serum albumin (BSA) was investigated in detail using fluorescence spectroscopy method. Quenching mechanism, the binding constants, and number of binding sites were determined. © 2016, Springer Science+Business Media New York.
引用
收藏
页码：427 / 430
页数：3
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