Life-threatening intoxication with methylene (bis(thiocyanate): Clinical picture and pitfalls. A case report

被引：10

作者：

Braun C. ^{[1
,3
]}

Birck R. ^{[1
]}

Singer M.V. ^{[2
]}

Schnuelle P. ^{[1
]}

van der Woude F.J. ^{[1
]}

Löhr M. ^{[2
]}

机构：

[1] Department of Medicine V (Nephrology/Endocrinology/Rheumatology), University Medical Center Mannheim

[2] Department of Medicine II (Gastroenterology/Hepatology/Infectious Diseases), University Medical Center Mannheim

[3] Départment de Médecine Interne et Néphrologie, Centre Hospitalier Kirchberg

来源：

BMC Emergency Medicine | / 6卷 / 1期

关键词：

Acute Liver Failure; Molecular Adsorbent Recirculate System; Primary Graft Dysfunction; Methemoglobin Level; Albumin Dialysis;

D O I：

10.1186/1471-227X-6-5

中图分类号：

学科分类号：

摘要：

Background: Methylene bis(thiocyanate) (MBT) is a microbiocidal agent mainly used in industrial water cooling systems and paper mills as an inhibitor of algae, fungi, and bacteria. Case presentation: We describe the first case of severe intoxication following inhalation of powder in an industrial worker. Profound cyanosis and respiratory failure caused by severe methemoglobinemia developed within several minutes. Despite immediate admission to the intensive care unit, where mechanical ventilation and hemodialysis for toxin elimination were initiated, multi-organ failure involving liver, kidneys, and lungs developed. While liver failure was leading, the patient was successfully treated with the MARS (molecular adsorbent recirculating system) procedure. Conclusion: Intoxication with MBT is a potentially life-threatening intoxication causing severe methemoglobinemia and multi-organ failure. Extracorporeal liver albumin dialysis (MARS) appears to be an effective treatment to allow recovery of hepatic function. © 2006 Braun et al; licensee BioMed Central Ltd.

引用

共 13 条

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[10]

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