Role of Wnt signaling and sclerostin in bone and as therapeutic targets in skeletal disorders

被引:0
|
作者
Francesca Marini
Francesca Giusti
Gaia Palmini
Maria Luisa Brandi
机构
[1] Italian Foundation for the Research on Bone Diseases,Fondazione FIRMO Onlus
[2] Villa Donatello Hospital,Donatello Bone Clinic
[3] University of Florence,Department of Experimental and Clinical Biomedical Sciences
来源
关键词
β-Catenin; Lipoprotein receptor–related protein 5 (LPR5); Sclerostin; gene; Wnt proteins; Wnt signaling pathway;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:213 / 238
页数:25
相关论文
共 50 条
  • [21] Role of Wnt-signaling inhibitors DKK-1 and sclerostin in bone fragility associated with Turner syndrome
    M. Chiarito
    L. Piacente
    N. Chaoul
    P. Pontrelli
    G. D’Amato
    A. Grandone
    G. Russo
    M. E. Street
    M. G. Wasniewska
    G. Brunetti
    M. F. Faienza
    Journal of Endocrinological Investigation, 2022, 45 : 1255 - 1263
  • [22] The role of β-adrenoceptor signaling in skeletal muscle: therapeutic implications for muscle wasting disorders
    Koopman, Rene
    Ryall, James G.
    Church, Jarrod E.
    Lynch, Gordon S.
    CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 2009, 12 (06): : 601 - 606
  • [23] Sclerostin and Wnt Signaling in Pediatric Renal Osteodystrophy
    Albrecht, Lauren V.
    Laster, Marciana
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2022, 33 (11): : 439 - 439
  • [24] Role of sclerostin in bone and cartilage and its potential as a therapeutic target in bone diseases
    Lewiecki, E. Michael
    THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2014, 6 (02) : 48 - 57
  • [25] Wnt signaling in bone metastasis: mechanisms and therapeutic opportunities
    Li, Xin
    Yang, Jing
    Bao, Minyue
    Zeng, Kan
    Fu, Shijin
    Wang, Chenglin
    Ye, Ling
    LIFE SCIENCES, 2018, 208 : 33 - 45
  • [26] Sclerostin Mediates Bone Response to Mechanical Unloading Through Antagonizing Wnt/β-Catenin Signaling
    Lin, Chuwen
    Jiang, Xuan
    Dai, Zhongquan
    Guo, Xizhi
    Weng, Tujun
    Wang, Jun
    Li, Yinghui
    Feng, Guoyin
    Gao, Xiang
    He, Lin
    JOURNAL OF BONE AND MINERAL RESEARCH, 2009, 24 (10) : 1651 - 1661
  • [27] Effect of the Wnt-Signaling Inhibitor Sclerostin and Bone Marrow Adipocytes on Multiple Myeloma
    Panaroni, Cristina
    Siu, Ka Tat
    Fulzele, Keertik S.
    Ramachandran, Janani
    Raje, Noopur
    BLOOD, 2016, 128 (22)
  • [28] Control of Bone Homeostasis by the Wnt Inhibitor Sclerostin
    Meghan E. McGee-Lawrence
    Mark W. Hamrick
    Current Molecular Biology Reports, 2016, 2 (3) : 141 - 148
  • [29] Wnt signaling in bone formation and its therapeutic potential for bone diseases
    Kim, Jeong Hwan
    Liu, Xing
    Wang, Jinhua
    Chen, Xiang
    Zhang, Hongyu
    Kim, Stephanie H.
    Cui, Jing
    Li, Ruidong
    Zhang, Wenwen
    Kong, Yuhan
    Zhang, Jiye
    Shui, Wei
    Lamplot, Joseph
    Rogers, Mary Rose
    Zhao, Chen
    Wang, Ning
    Rajan, Prashant
    Tomal, Justin
    Statz, Joseph
    Wu, Ningning
    Luu, Hue H.
    Haydon, Rex C.
    He, Tong-Chuan
    THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE, 2013, 5 (01) : 13 - 31
  • [30] The role of Wnt signaling in bone and mineral metabolism
    Bodine P.V.N.
    Robinson J.A.
    Bhat R.A.
    Billiard J.
    Bex F.J.
    Komm B.S.
    Clinical Reviews in Bone and Mineral Metabolism, 2006, 4 (2): : 73 - 96