Chemo-Bio Catalyzed Synthesis of R-1-Phenylethyl Acetate over Bimetallic PdZn Catalysts, Lipase, and Ru/Al2O3. Part II

被引：4

作者：

Kirilin, A. ^{[1
,4
]}

Maki-Arvela, P. ^{[1
]}

Kordas, K. ^{[2
]}

Leino, A. -R. ^{[2
]}

Shchukarev, A. ^{[3
]}

Bostrom, D.

Mikkola, J-P. ^{[1
,3
]}

Kustov, L. M. ^{[1
]}

Salmi, T. O. ^{[1
]}

Murzin, D. Yu. ^{[1
]}

机构：

[1] Abo Akad Univ, Proc Chem Ctr, Lab Ind Chem & React Engn, Turku, Finland

[2] Univ Oulu, Microelect & Mat Phys Labs, Dept Elect & Informat Engn, Oulu, Finland

[3] Umea Univ, Dept Chem, Chem Biol Ctr, Umea, Sweden

[4] Zelinsky Inst Organ Chem, Moscow 119991, Russia

来源：

KINETICS AND CATALYSIS | 2011年 / 52卷 / 01期

基金：

芬兰科学院;

关键词：

ACETOPHENONE; RUTHENIUM;

D O I：

10.1134/S0023158411010095

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

One-pot synthesis of R-1-phenyethylacetate at 70 degrees C was investigated using three different catalysts simultaneously, namely a bimetallic PdZn/Al2O3 as a hydrogenation catalyst, an immobilized lipase as an acylation catalyst and Ru/Al2O3 as a racemization catalyst. The most active bimetallic catalyst was PdZn/Al2O3 calcined at 300 degrees C and reduced at 400 degrees C, whereas the most selective although less active catalyst was the one being calcined and reduced at 500 degrees C. The highest selectivity to R-1-phenylethyl acetate over this catalyst was 32 at 48% conversion. Ru/Al2O3 was confirmed to have a positive effect on the formation of the desired product, although it was not very active in the racemization during one-pot synthesis.

引用

页码：77 / 81

页数：5

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