Chromosomal Instability Associated with Global DNA Hypomethylation is Associated with the Initiation and Progression of Esophageal Squamous Cell Carcinoma

被引:2
作者
Hiroyuki Kawano
Hiroshi Saeki
Hiroyuki Kitao
Yasuo Tsuda
Hajime Otsu
Koji Ando
Shuhei Ito
Akinori Egashira
Eiji Oki
Masaru Morita
Yoshinao Oda
Yoshihiko Maehara
机构
[1] Kyushu University,Department of Surgery and Science, Graduate School of Medical Sciences
[2] Kyushu University,Department of Molecular Oncology, Graduate School of Medical Sciences
[3] Kyushu University,Department of Anatomic Pathology, Graduate School of Medical Sciences
来源
Annals of Surgical Oncology | 2014年 / 21卷
关键词
Esophageal Squamous Cell Carcinoma; Methylation Level; Chromosomal Instability; Single Nucleotide Polymorphism Array; Noncancerous Tissue;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:696 / 702
页数:6
相关论文
共 122 条
  • [31] Estecio MR(2002)Biologic and clinical significance of squamous epithelial dysplasia of the esophagus Surgery. 131 S22-670
  • [32] Doshi K(2009)SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas Nat Genet. 41 1238-1566
  • [33] Ikeda K(2012)Silencing SOX2 induced mesenchymal–epithelial transition and its expression predicts liver and lymph node metastasis of CRC patients PLoS One. 7 e41335-216
  • [34] Shiraishi K(2000)AIS is an oncogene amplified in squamous cell carcinoma Proc Natl Acad Sci USA. 97 5462-7651
  • [35] Eguchi A(2013)FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma J Clin Investig. 123 3525-1412
  • [36] Igarashi S(2011)Fibrous stroma is associated with poorer prognosis in lung squamous cell carcinoma patients J Thorac Oncol. 6 1460-781
  • [37] Suzuki H(2012)Activation of multiple cancer pathways and tumor maintenance function of the 3q amplified oncogene FNDC3B Cell Cycle. 11 1773-undefined
  • [38] Niinuma T(2012)Prognostic significance of cyclinD1 amplification and the co-alteration of cyclinD1/pRb/ppRb in patients with esophageal squamous cell carcinoma Dis Esophagus. 25 664-undefined
  • [39] Ogino S(2012)Genomic copy-number alterations of MYC and FHIT genes are associated with survival in esophageal squamous-cell carcinoma Cancer Sci. 103 1558-undefined
  • [40] Nosho K(2004)High frequency of CDKN2A alterations in esophageal squamous cell carcinoma from a high-risk Chinese population Genes Chromosomes Cancer. 39 205-undefined