Chromosomal Instability Associated with Global DNA Hypomethylation is Associated with the Initiation and Progression of Esophageal Squamous Cell Carcinoma

[21] Brambrink T(2004)Mutant p53 gain of function in two mouse models of Li–Fraumeni syndrome Cell. 119 847-8

[22] Suzuki K(2010)A common gain of function of p53 cancer mutants in inducing genetic instability Oncogene. 29 949-1740

[23] Suzuki I(2013)p53 mutations in cancer Nat Cell Biol. 15 2-1156

[24] Leodolter A(2011)Copy-neutral loss of heterozygosity at the p53 locus in carcinogenesis of esophageal squamous cell carcinomas associated with p53 mutations Clin Cancer Res. 17 1731-1063

[25] Nishida N(2010)Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma BMC Genomics. 11 576-S27

[26] Kudo M(2007)p53 gene mutations in esophageal squamous cell carcinoma and their relevance to etiology and pathogenesis: results in Japan and comparisons with other countries Cancer Sci. 98 1152-1242

[27] Nishimura T(2013)DNA methylation pyrosequencing assay is applicable for the assessment of epigenetic active environmental or clinical relevant chemicals Biomed Res Int. 2013 486072-5467

[28] Cordaux R(2010)MixHMM: inferring copy number variation and allelic imbalance using SNP arrays and tumor samples mixed with stromal cells PLoS One. 5 e10909-3538

[29] Batzer MA(2011)Interleukin-6 promotes tumorigenesis by altering DNA methylation in oral cancer cells Int J Cancer. 129 1053-1467

[30] Yang AS(2011)Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis PLoS Genet. 7 e1001356-1781

[21] Brambrink T(2004)Mutant p53 gain of function in two mouse models of Li–Fraumeni syndrome Cell. 119 847-8

[22] Suzuki K(2010)A common gain of function of p53 cancer mutants in inducing genetic instability Oncogene. 29 949-1740

[23] Suzuki I(2013)p53 mutations in cancer Nat Cell Biol. 15 2-1156

[24] Leodolter A(2011)Copy-neutral loss of heterozygosity at the p53 locus in carcinogenesis of esophageal squamous cell carcinomas associated with p53 mutations Clin Cancer Res. 17 1731-1063

[25] Nishida N(2010)Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma BMC Genomics. 11 576-S27

[26] Kudo M(2007)p53 gene mutations in esophageal squamous cell carcinoma and their relevance to etiology and pathogenesis: results in Japan and comparisons with other countries Cancer Sci. 98 1152-1242

[27] Nishimura T(2013)DNA methylation pyrosequencing assay is applicable for the assessment of epigenetic active environmental or clinical relevant chemicals Biomed Res Int. 2013 486072-5467

[28] Cordaux R(2010)MixHMM: inferring copy number variation and allelic imbalance using SNP arrays and tumor samples mixed with stromal cells PLoS One. 5 e10909-3538

[29] Batzer MA(2011)Interleukin-6 promotes tumorigenesis by altering DNA methylation in oral cancer cells Int J Cancer. 129 1053-1467

[30] Yang AS(2011)Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis PLoS Genet. 7 e1001356-1781