Chromosomal Instability Associated with Global DNA Hypomethylation is Associated with the Initiation and Progression of Esophageal Squamous Cell Carcinoma

被引:2
作者
Hiroyuki Kawano
Hiroshi Saeki
Hiroyuki Kitao
Yasuo Tsuda
Hajime Otsu
Koji Ando
Shuhei Ito
Akinori Egashira
Eiji Oki
Masaru Morita
Yoshinao Oda
Yoshihiko Maehara
机构
[1] Kyushu University,Department of Surgery and Science, Graduate School of Medical Sciences
[2] Kyushu University,Department of Molecular Oncology, Graduate School of Medical Sciences
[3] Kyushu University,Department of Anatomic Pathology, Graduate School of Medical Sciences
来源
Annals of Surgical Oncology | 2014年 / 21卷
关键词
Esophageal Squamous Cell Carcinoma; Methylation Level; Chromosomal Instability; Single Nucleotide Polymorphism Array; Noncancerous Tissue;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:696 / 702
页数:6
相关论文
共 122 条
  • [1] Allum WH(2009)Long-term results of a randomized trial of surgery with or without preoperative chemotherapy in esophageal cancer J Clin Oncol. 27 5062-5067
  • [2] Stenning SP(2003)Esophageal cancer N Engl J Med. 349 2241-2252
  • [3] Bancewicz J(2008)Advances in esophageal cancer surgery in Japan: an analysis of 1000 consecutive patients treated at a single institute Surgery 143 499-508
  • [4] Enzinger PC(2010)Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: epidemiology, clinical findings, and prevention Int J Clin Oncol. 15 126-134
  • [5] Mayer RJ(2010)Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: molecular mechanisms of carcinogenesis Int J Clin Oncol. 15 135-144
  • [6] Morita M(2002)DNA methylation in cancer: too much, but also too little Oncogene. 21 5400-5413
  • [7] Yoshida R(2003)Induction of tumors in mice by genomic hypomethylation Science. 300 489-492
  • [8] Ikeda K(2005)Global loss of imprinting leads to widespread tumorigenesis in adult mice Cancer Cell. 8 275-285
  • [9] Morita M(2006)Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage Cancer Cell. 9 199-207
  • [10] Kumashiro R(2013)Unique association between global DNA hypomethylation and chromosomal alterations in human hepatocellular carcinoma PLoS One. 8 e72312-703