Acute quadriplegic myopathy following autologous peripheral blood stem cell transplantation for breast cancer

被引:0
作者
J Samuelsson
H Zackrisson
L Tokics
P Ljungman
E Lidbrink
P Pircher
L Larsson
机构
[1] Huddinge University Hospital,Department of Hematology
[2] Huddinge,Department of Anesthesiology
[3] Karolinska Hospital,Department of Anesthesiology and Critical Care
[4] Huddinge University Hospital,Department of Oncology
[5] Huddinge University Hospital,undefined
[6] Noll Physiological Research Center,undefined
[7] University Park,undefined
[8] State College,undefined
来源
Bone Marrow Transplantation | 1999年 / 23卷
关键词
autologous stem cell transplantation; breast cancer; myopathy; myosin; steroids;
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摘要
Autologous peripheral blood stem cell transplantation (APSCT) is increasingly used in the treatment of breast cancer. We report a patient who experienced septic shock, and after treatment with antibiotics, high-dose corticosteroids and mechanical ventilation due to respiratory insufficiency, developed quadriplegia. Electroneurophysiological examination, as well as a muscle biopsy, showed a typical picture of acute quadriplegic myopathy with loss of thick filament proteins. This is, to the best of our knowledge, the first reported case of this complication following APSCT.
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页码:835 / 837
页数:2
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