Evaluation of tramadol human pharmacokinetics and safety after co-administration of magnesium ions in randomized, single- and multiple-dose studies

[1] Fornasari D(2017)Pharmacotherapy for neuropathic pain. A review Pain Ther 6 25-33

[2] Knezevic NN(2017)Treatment of chronic low back pain - new approaches on the horizon J Pain Res 10 1111-1123

[3] Mandalia S(2016)Twenty-five years of prescription opioid use in Australia: a whole-of-population analysis using pharmaceutical claims Br J Clin Pharmacol 82 255-267

[4] Raasch J(2018)Opioids out of control Br J Clin Pharmacol 84 813-815

[5] Knezevic I(2002)Magnesium increases morphine analgesic effect in different experimental models of pain Anesthesiol 96 627-632

[6] Candido KD(2008)Magnesium ions and opioid agonist activity in streptozotocin-induced hyperalgesia Pharmacol 82 180-186

[7] Karanges EA(2009)Magnesium ions and opioid agonists in vincristine-induced neuropathy Pharmacol Rep 61 1096-1104

[8] Blanch B(2014)Additive effect of combined application of magnesium and MK-801 on analgesic action of morphine Pharmacol 93 113-119

[9] Buckley NA(2016)Micronized organic magnesium salts enhance opioid analgesia in rats PLoS ONE 11 e0161776-836

[10] Pearson SA(1998)Antinociceptive potentiation and attenuation of tolerance by intrathecal co-infusion of magnesium sulfate and morphine in rats Anesth Analg 86 830-718

[1] Fornasari D(2017)Pharmacotherapy for neuropathic pain. A review Pain Ther 6 25-33

[2] Knezevic NN(2017)Treatment of chronic low back pain - new approaches on the horizon J Pain Res 10 1111-1123

[3] Mandalia S(2016)Twenty-five years of prescription opioid use in Australia: a whole-of-population analysis using pharmaceutical claims Br J Clin Pharmacol 82 255-267

[4] Raasch J(2018)Opioids out of control Br J Clin Pharmacol 84 813-815

[5] Knezevic I(2002)Magnesium increases morphine analgesic effect in different experimental models of pain Anesthesiol 96 627-632

[6] Candido KD(2008)Magnesium ions and opioid agonist activity in streptozotocin-induced hyperalgesia Pharmacol 82 180-186

[7] Karanges EA(2009)Magnesium ions and opioid agonists in vincristine-induced neuropathy Pharmacol Rep 61 1096-1104

[8] Blanch B(2014)Additive effect of combined application of magnesium and MK-801 on analgesic action of morphine Pharmacol 93 113-119

[9] Buckley NA(2016)Micronized organic magnesium salts enhance opioid analgesia in rats PLoS ONE 11 e0161776-836

[10] Pearson SA(1998)Antinociceptive potentiation and attenuation of tolerance by intrathecal co-infusion of magnesium sulfate and morphine in rats Anesth Analg 86 830-718