PEGylated PAMAM Dendrimer-Doxorubicin Conjugates: In Vitro Evaluation and In Vivo Tumor Accumulation

被引：0
|
作者：
Saijie Zhu
Minghuang Hong
Lihong Zhang
Guotao Tang
Yanyan Jiang
Yuanying Pei
机构：
[1] Fudan Univeristy,Department of Pharmaceutics, School of Pharmacy
来源：
Pharmaceutical Research | 2010年 / 27卷
关键词：
acid-sensitive linkage; cellular uptake; doxorubicin; poly(amidoamine) dendrimer; poly(ethylene glycol);
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：161 / 174
页数：13
相关论文
共 50 条
  • [21] In vitro and in vivo anti-tumor activities of nanoparticles based on doxorubicin-PLGA conjugates
    Department of Biological Sciences, Korea Adv. Inst. Sci. and Technol., Taejon 305-701, Korea, Republic of
    American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, 2000, 41 (01): : 992 - 993
  • [22] In vitro and in vivo anti-tumor activities of nanoparticles based on doxorubicin-PLGA conjugates
    Yoo, HS
    Lee, KH
    Oh, JE
    Park, TG
    JOURNAL OF CONTROLLED RELEASE, 2000, 68 (03) : 419 - 431
  • [23] Cationic Poly-L-lysine Dendrimer Complexes Doxorubicin and Delays Tumor Growth in Vitro and in Vivo
    Al-Jamal, Khuloud T.
    Al-Jamal, Wafa' T.
    Wang, Julie T. -W.
    Rubio, Noelia
    Buddle, Joanna
    Gathercole, David
    Zloh, Mire
    Kostarelos, Kostas
    ACS NANO, 2013, 7 (03) : 1905 - 1917
  • [24] KETOCONAZOLE-PAMAM DENDRIMER SUPRAMOLECULAR COMPLEX FOR PROLONGED DELIVERY BY IN VITRO AND IN VIVO STUDIES
    Kacso, Irina
    Baldea, Ioana
    Miclaus, Maria
    Mot, Augustin
    Moldovan, Remus
    Martin, Flavia
    STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA, 2023, 68 (04): : 137 - 154
  • [25] Synthesis and biological evaluation of novel asymmetric bow-tie PAMAM dendrimer-based tumor-targeting drug conjugates
    Wang, Tao
    Teng, Yuhan Gary
    Wei, Longfei
    Li, Wei
    Ojima, Iwao
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
  • [26] Brucine PEGylated nanoemulsion: In vitro and in vivo evaluation
    Elsewedy, Heba S.
    Aldhubiab, Bandar E.
    Mahdy, Mahmoud A.
    Elnahas, Hanan M.
    COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2021, 608
  • [27] Synthesis and In Vivo Antitumor Efficacy of PEGylated Poly(L-lysine) Dendrimer-Camptothecin Conjugates
    Fox, Megan E.
    Guillaudeu, Steve
    Frechet, Jean M. J.
    Jerger, Katherine
    Macaraeg, Nichole
    Szoka, Francis C.
    MOLECULAR PHARMACEUTICS, 2009, 6 (05) : 1562 - 1572
  • [28] The interaction of dendrimer-doxorubicin conjugates with a model pulmonary epithelium and their cosolvent-free, pseudo-solution formulations in pressurized metered-dose inhalers
    Zhong, Qian
    Humia, Bruno V.
    Punjabi, Alisha R.
    Padilha, Francine F.
    da Rocha, Sandro R. P.
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 109 : 86 - 95
  • [29] Synthesis of CpM(CO)3-DAB and -PAMAM Dendrimer Conjugates and Preliminary Evaluation of Their Biological Activity
    Hu, Wanning
    Hoyer, Jan
    Neundorf, Ines
    Govender, Preshendren
    Smith, Gregory S.
    Schatzschneider, Ulrich
    EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2015, (09) : 1505 - 1510
  • [30] Design, synthesis, and biological evaluations of novel PAMAM dendrimer-based tumor-targeting taxoid conjugates
    Wei, Longfei
    Wang, Tao
    Bahl, Sonali
    Teng, Yu-Han
    Ojima, Iwao
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 250
12345