The Impact of Bariatric Surgery on Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis

被引：0
作者：
Daniel Skubleny
Noah J. Switzer
Richdeep S. Gill
Mark Dykstra
Xinzhe Shi
Margaret A. Sagle
Christopher de Gara
Daniel W. Birch
Shahzeer Karmali
机构：
[1] University of Alberta,Faculty of Medicine and Dentistry
[2] University of Alberta,Department of Surgery, Faculty of Medicine and Dentistry
[3] Royal Alexandra Hospital,Centre for the Advancement of Minimally Invasive Surgery (CAMIS)
[4] University of Alberta,Department of Obstetrics and Gynecology
[5] University of Alberta,2D, Walter C Mackenzie Health Sciences Centre
来源：
Obesity Surgery | 2016年 / 26卷
关键词：
Bariatric surgery; Obesity; Polycystic ovary syndrome;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Bariatric surgery has been proven to be a successful management strategy for morbid obesity, but limited studies exist on its effect on polycystic ovary syndrome (PCOS). A comprehensive search of electronic databases was completed. Meta-analysis was performed on PCOS, hirsutism, and menstrual irregularity outcomes following bariatric surgery. Thirteen primary studies involving a total of 2130 female patients were identified. The incidence of PCOS preoperatively was 45.6 %, which significantly decreased to 6.8 % (P < 0.001) and 7.1 % (P < 0.0002) at 12-month follow-up and study endpoint, respectively. The incidences of preoperative menstrual irregularity and hirsutism both significantly decreased at 12-month and at study end follow-up. Bariatric surgery effectively attenuates PCOS and its clinical symptomatology including hirsutism and menstrual irregularity in severely obese women.
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页码：169 / 176
页数：7
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