Role of chest radiography in the diagnosis of allergic bronchopulmonary aspergillosis in adult patients with cystic fibrosis

被引：10

作者：

Cortese G. ^{[1
]}

Malfitana V. ^{[1
]}

Placido R. ^{[1
]}

Ferrari A. ^{[1
]}

Grosso B. ^{[2
]}

De Rose V. ^{[2
]}

Nespoli P. ^{[3
]}

Fava C. ^{[3
]}

机构：

[1] Servizio di Radiologia, Ospedale degli Infermi, I-13900 Biella

[2] Clinica di Malattie dell'Apparato Respiratorio, Università degli Studi di Torino

[3] S.C.D.U. Radiologia Diagnostica, Dipartimento di Scienze Cliniche e Biologiche, Università degli Studi di Torino, I-10043 Orbassano, A.S.O. S. L. Gonzaga

来源：

La radiologia medica | 2007年 / 112卷 / 5期

关键词：

ABPA; Chest X-ray; Cystic fibrosis in adult patients;

D O I：

10.1007/s11547-007-0169-x

中图分类号：

学科分类号：

摘要：

Purpose. This study aimed to verify the usefulness of chest radiography in the diagnosis of allergic bronchopulmonary aspergillosis (ABPA) in adult patients with cystic fibrosis. Materials and methods. Eleven patients (with a total of 14 episodes) affected by ABPA were selected from among subjects attending a Regional Cystic Fibrosis Centre. For each episode, we retrospectively reviewed the baseline chest radiographs obtained before the diagnosis of ABPA, those obtained during the course of ABPA and those obtained during follow-up. Radiographs were assessed for the presence of bronchial wall thickening, bronchiectasis, infiltrates, atelectasis, mucoid impaction, lymphadenopathy, pleural effusion and fluid levels. Radiographic findings that had appeared at the time of ABPA diagnosis and disappeared after treatment were considered related to ABPA and thus useful for a correct diagnosis of the disease. Chest radiograph abnormalities were compared with changes on the respiratory function tests [forced expiratory volume in 1 s (FEV1)] during the different stages of the disease. Results. Radiographic findings at the time of ABPA diagnosis appeared to have deteriorated in 8/14 cases when compared with the baseline films; after treatment, the radiographic findings deteriorated in 6/14 cases and improved in 6/14. The most significant among the radiographic signs considered (infiltrates and mucoid impaction) appeared at the time of ABPA diagnosis in 7/14 and 4/14 cases, respectively, and in some patients, they were also present at baseline and persisted during follow-up. FEV1 values were significantly decreased (>10%) in 9/14 cases at the time of ABPA diagnosis. Conclusions. Our results demonstrate the limited usefulness of chest radiography in the diagnosis of ABPA in patients with cystic fibrosis. The most significant abnormalities are nonspecific and commonly seen on baseline films in cystic fibrosis without ABPA and persist after treatment in most cases. © 2007 Springer-Verlag.

引用

页码：626 / 636

页数：10

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