Serum lipid profile in patients with acute myocardial infarction

被引:8
作者
Nigam P.K. [1 ]
Narain V.S. [1 ]
Hasan M. [1 ]
机构
[1] Department of Cardiology, King George's Medical University
关键词
Lipids; Lipoproteins; Myocardial Infarction;
D O I
10.1007/BF02872393
中图分类号
学科分类号
摘要
Serum lipids and lipoproteins were estimated in 29 patients with acute myocardial infarction during acute phase (day 1,2,3), predischarge and after three months. Serum total lipids, total cholesterol (TC) and LDL-cholesterol (LDLc) showed no significant change during the hospital stay and three months followup. HDL-cholesterol (HDLc), however, started falling from day 2 onwards with statistically significant reduction at pre-discharge and remained so at 3 months. The ratios of TC/HDLc and LDLc/HDLc showed significant increase on predischarge day as compared to day 1. Serum triglycerides also showed an increasing trend after myocardial infarction with a significant increase on day 3 and predischarge as compared to day 1. It is concluded that the optimum time for assessment of serum lipid profile in patients with myocardial infarction seems to be within 24 hours of the acute episode.
引用
收藏
页码:67 / 70
页数:3
相关论文
共 27 条
[1]  
Biorch G., Blomquist G., Sievers J., Cholesterol values in patients with myocardial infarction and normal control group, Acta. Med. Scand., 156, pp. 493-497, (1957)
[2]  
Bjorntrop P., Malmcrone R., Serum cholesterol in patient with myocardial infarction in younger ages, Acta. Med. Scand., 168, pp. 151-155, (1960)
[3]  
Dodds C., Mills G.L., Influence of myocardial infarction on plasma lipoprotein concentration, Lancet, 1, pp. 1160-1163, (1959)
[4]  
Tibblin G., Cramer K., Serum lipids during the course of acute myocardial infarction and one year afterwards, Acta Med. Scand., 174, pp. 451-455, (1963)
[5]  
Fyfe T., Baxter R.H., Cochran K.M., Booth E.M., Plasma lipid changes'after myocardial infarction, Lancet, 2, pp. 997-1001, (1971)
[6]  
Kirkeby K., Disturbances in serum lipids and in their fatty' acid composition following acute myocardial infarction, Acta Med. Scand., 192, pp. 523-528, (1972)
[7]  
Avogaro A., Bittilin Bon G., Cazzalato C., Quinci G.B., Sanson A., Sparla H., Zagatti G.C., Variations in apolipoproteins B and A during the course of myocardial infarction, Eur. J. Clin. Invest, 8, pp. 121-129, (1978)
[8]  
Ballantyne F.C., Melville D.A., Mc Kenna J.P., Morrison B.A., Ballantyne D., Response of plasma lipoproteins and acute phase proteins to myocardial infarction, Clin. Chim. Acta, 99, pp. 85-92, (1979)
[9]  
Ryder R.E.J., Hayes T.M., Mulligan I.P., Kingswood J.C., Williams S., Owens D.R., How soon after myocardial infarction should plasma lipid values be assessed?, Br. Med. J., 289, pp. 1651-1653, (1984)
[10]  
Jackson R., Scragg R., Marshall R., White, O'Brien K., Small C., Changes is serum lipid concentrations during first 24, hours after myocardial infarction, Br. Med. J., 294, pp. 1588-1589, (1987)