The Role of Notch Signaling in Adult Neurogenesis

被引：0
作者：
Itaru Imayoshi
Ryoichiro Kageyama
机构：
[1] Kyoto University,Institute for Virus Research
[2] Kyoto University,The Hakubi Center
[3] Precursory Research for Embryonic Science and Technology (PRESTO),Japan Science and Technology Agency
[4] Core Research for Evolutional Science and Technology (CREST),Japan Science and Technology Agency
来源：
Molecular Neurobiology | 2011年 / 44卷
关键词：
Notch signaling; Rbpj; Hes1; Hes5; Adult neurogenesis; Neural stem cells;
D O I：
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学科分类号：
摘要：
Neurogenesis occurs throughout adulthood in the mammalian brain. Newly born neurons are incorporated into the functional networks of both the olfactory bulb and the hippocampal dentate gyrus, and there is growing evidence that adult neurogenesis is important for various brain functions. Continuous neurogenesis is achieved by the coordinated proliferation and differentiation of adult neural stem cells. In this review, we discuss the recent findings concerning the roles of Notch signaling in adult neural stem cells.
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页码：7 / 12
页数：5
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