Effect of Sodium Bicarbonate Amount on In Vitro Indomethacin Release from Self-Setting Carbonated-Apatite Cement

被引：0
作者：
Makoto Otsuka
Yoshihisa Matsuda
Zeren Wang
Jeffrey L. Fox
William I. Higuchi
机构：
[1] Kobe University,Department of Pharmaceutical Technology
[2] University of Utah,Department of Pharmaceutics and Pharmaceutical Chemistry
来源：
Pharmaceutical Research | 1997年 / 14卷
关键词：
drug delivery system; biomaterials; self-setting bioactive carbonate apatite cement; indomethacin release; mercury porosimetry;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. In the present study, to develop a drug delivery system with higher bioacitivity in hard tissues by using the self-setting bioactive carbonate apatite cement, we have investigated the effects of sodium bicarbonate content on thein vitro drug release from a self-setting bioactive carbonate apatite cement containing indomethacin (IMC).
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页码：444 / 449
页数：5
相关论文
共 58 条
  • [1] Hyakuna K.(1990)undefined Biomed. Mater. Res. 24 471-488
  • [2] Yamamuro T.(1993)undefined J. Applied Biomaterials 4 29-38
  • [3] Kotoura Y.(1995)undefined Sciences 267 1796-1799
  • [4] Oka M.(1990)undefined Chem. Pharm. Bull. 38 3500-3502
  • [5] Nishimura N.(1994)undefined J. Pharm. Sci. 83 259-263
  • [6] Taguchi Y.(1994)undefined J. Pharm. Sci. 83 611-615
  • [7] Yamamuro T.(1994)undefined J. Pharm. Sci. 83 1569-1573
  • [8] Corltz B. R.(1995)undefined J. Pharm. Sci. 84 733-736
  • [9] Ison I. C.(1990)undefined J. Pharm. Sci. 79 510-514
  • [10] Fulmer M. T.(1991)undefined J. Am. Ceram. Soc. 74 1739-1741
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