Bufalin inhibits CYP3A4 activity in vitro and in vivo

被引:0
作者
Hai-yun Li
Wen Xu
Xi Zhang
Wei-dong Zhang
Li-wei Hu
机构
[1] School of Pharmacy,Department of Natural Medicinal Chemistry
[2] Second Military Medical University,Department of Pharmacy
[3] Changzheng Hospital,undefined
[4] Second Military Medical University,undefined
[5] School of Pharmacy,undefined
[6] Shanghai Jiao Tong University,undefined
来源
Acta Pharmacologica Sinica | 2009年 / 30卷
关键词
bufalin; cytochrome CYP3A4; inhibitory interaction; pharmacokinetics;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:646 / 652
页数:6
相关论文
共 106 条
[1]  
Luo G(2002)CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes Drug Metab Dispos 30 795-804
[2]  
Cunningham M(2000)Human cytochrome P-450 3A4: Drug Metab Dispos 28 360-6
[3]  
Kim S(2008) drug drug interaction patterns are substrate-dependent Biochem Pharmacol 75 1426-37
[4]  
Burn T(2006)Flavonoids diosmetin and luteolin inhibit midazolam metabolism by human liver microsomes and recombinant CYP3A4 and CYP3A5 enzymes Drug Metab Dispos 34 1779-85
[5]  
Lin J(2007)Metabolism of endosulfan-α by human liver microsomes and its utility as a simultaneous Am J Clin Nutr 85 269S-76S
[6]  
Sinz M(2002) probe for CYP2B6 and CYP3A4 Life Sci 72 699-709
[7]  
Wang RW(2004)Multivitamin and multimineral dietary supplements: definitions, characterization, bioavailability, and drug interactions Drug Metab Pharmacokinet 19 280-9
[8]  
Newton DJ(2007)Effects of Chan Su, a traditional Chinese medicine, on the calcium transients of isolated cardiomyocytes: cardiotoxicity due to more than Na, K-ATPase blocking J Am Med Dir Assoc 8 248-52
[9]  
Liu N(2004)Effects of continuous ingestion of green tea or grape seed extracts on the pharmacokinetics of midazolam Toxicol Rev 23 239-49
[10]  
Atkins WM(2003)Do herbal agents have a place in the treatment of sleep problems in long-term care? Clin Chim Acta 330 179-84